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先天性心脏病手术后急性神经系统并发症的发生率及结局

Frequency and Outcome of Acute Neurologic Complications after Congenital Heart Disease Surgery.

作者信息

Jafri Sidra Kaleem, Ehsan Lubaina, Abbas Qalab, Ali Fatima, Chand Prem, Ul Haque Anwar

机构信息

Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.

出版信息

J Pediatr Neurosci. 2017 Oct-Dec;12(4):328-331. doi: 10.4103/jpn.JPN_87_17.

DOI:10.4103/jpn.JPN_87_17
PMID:29675070
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5890551/
Abstract

OBJECTIVES

To determine the frequency and immediate outcome of acute neurologic complications (ANCs) in children undergoing congenital heart surgery (CHS).

MATERIALS AND METHODS

In this retrospective study, all patients undergoing CHS at our hospital from January 2007 to June 2016 were included. Patients were followed up for the development of seizures, altered level of consciousness (ALOC), abnormal movements, and stroke. Results are presented as mean with standard deviation and frequency with percentages.

RESULTS

Of 2000 patients who underwent CHS at our center during the study, 35 patients (1.75%) developed ANC. Seizures occurred in 28 (80%), ALOC in 5 (14%), clinical stroke in 2, brain death in 6 patients. Antiepileptic drugs (AEDs) were started in 32 patients, of which 13 patients required more than one AED. Mean length of stay was 10 ± 7.36 days. Of 35 patients who developed ANC, 7 expired during the study.

CONCLUSION

Neurological complications are scarce but significant morbidity after CHS at our center.

摘要

目的

确定接受先天性心脏病手术(CHS)的儿童急性神经系统并发症(ANC)的发生率及近期预后。

材料与方法

在这项回顾性研究中,纳入了2007年1月至2016年6月在我院接受CHS的所有患者。对患者进行随访,观察癫痫发作、意识水平改变(ALOC)、异常运动和中风的发生情况。结果以均值±标准差及频率(百分比)表示。

结果

在研究期间,我院中心接受CHS的2000例患者中,35例(1.75%)发生了ANC。癫痫发作28例(80%),ALOC 5例(14%),临床中风2例,脑死亡6例。32例患者开始使用抗癫痫药物(AED),其中13例患者需要不止一种AED。平均住院时间为10±7.36天。在发生ANC的35例患者中,7例在研究期间死亡。

结论

在我们中心,神经系统并发症在CHS后虽少见但具有显著的发病率。

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