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用于周边角膜和角膜缘重建的冷冻保存角膜缘板层角膜移植术。

Cryopreserved limbal lamellar keratoplasty for peripheral corneal and limbal reconstruction.

作者信息

Xie Hua-Tao, Li Jing, Liu Yang, Jiang Dong-Ling, Shen Rui-Fen, Zhang Ming-Chang

机构信息

Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Schepens Eye Research Institute, Massachusetts Eye and Ear, Harvard Medical School, Boston 02114, USA.

出版信息

Int J Ophthalmol. 2018 Apr 18;11(4):699-702. doi: 10.18240/ijo.2018.04.27. eCollection 2018.

Abstract

This study aimed to evaluate the outcomes and described the recovery process of cryopreserved limbal lamellar keratoplasty (CLLK) for peripheral corneal and limbal diseases. Thirteen eyes of 12 patients with a mean age of 41±23.9y were included. The average follow-up was 12.1±5.6mo. Stable ocular surface was achieved in all eyes at last follow-up. Epithelialization originated from both recipient and graft in 9 eyes. We conclude that CLLK compensates for the shortage of donor corneas and cryopreserved limbal grafts provide epithelialization sources in ocular surface reconstruction.

摘要

本研究旨在评估深低温保存角膜缘板层角膜移植术(CLLK)治疗周边角膜及角膜缘疾病的疗效,并描述其恢复过程。纳入12例患者的13只眼,平均年龄41±23.9岁。平均随访时间为12.1±5.6个月。末次随访时所有术眼均获得稳定的眼表。9只眼的上皮化来源于植床和植片。我们得出结论,CLLK弥补了供体角膜的短缺,深低温保存的角膜缘植片为眼表重建提供了上皮化来源。

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1
Keratolimbal allograft.角膜缘移植片
Curr Opin Ophthalmol. 2017 Jul;28(4):377-381. doi: 10.1097/ICU.0000000000000374.
3
Global Survey of Corneal Transplantation and Eye Banking.全球角膜移植与眼库调查
JAMA Ophthalmol. 2016 Feb;134(2):167-73. doi: 10.1001/jamaophthalmol.2015.4776.
8
Management of pediatric corneal limbal dermoids.小儿角膜缘皮样瘤的管理
Clin Ophthalmol. 2013;7:607-14. doi: 10.2147/OPTH.S38663. Epub 2013 Mar 28.

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