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患者对压力性尿失禁的尿道填充注射疗法和中段尿道吊带手术的看法。

Patients' perspectives on urethral bulk injection therapy and mid-urethral sling surgery for stress urinary incontinence.

作者信息

Casteleijn Fenne M, Zwolsman Sandra E, Kowalik Claudia R, Roovers Jan-Paul P W R

机构信息

Department of Obstetrics and Gynecology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

出版信息

Int Urogynecol J. 2018 Sep;29(9):1249-1257. doi: 10.1007/s00192-018-3644-0. Epub 2018 Apr 19.

Abstract

INTRODUCTION AND HYPOTHESIS

The aim of this study was to identify all treatment decision factors that determined the preference for peri-urethral bulk injection therapy (PBI) or mid-urethral sling (MUS) surgery in patients with primary stress urinary incontinence (SUI). Second, we explored what patients expect from treatment for SUI and whether patients would consider PBI as a primary treatment option.

METHODS

In a qualitative design, 20 semi-structured, face-to-face interviews were conducted in women with primary SUI. Exclusion criteria were: previous PBI or MUS surgery; predominating urgency. Interviews were guided by three open-ended questions and a topic list. PBI treatment and MUS surgery were described in detail, and the efficacy was stated as 70% and 90%, respectively. Data saturation was reached when no new treatment decision factors were identified in three consecutive interviews. Interviews were audiotaped and fully transcribed. Thematic analysis by a coding process was done independently by two researchers.

RESULTS

Sixteen procedural, personal, professional, social and external treatment decision factors were identified. Regarding expectations about treatment for SUI, women believed 'becoming dry' was wishful thinking. The majority of patients accepted a small degree of persistent urinary incontinence after treatment. Regardless of their treatment preference, patients indicated that women should be informed about PBI as a primary treatment option.

CONCLUSION

Patients with primary SUI are open to PBI as an alternative treatment option even with lower cure rates compared with MUS surgery performed under general or spinal anesthesia. Patients indicated that women with primary SUI seeking treatment should be informed about PBI as a treatment option.

摘要

引言与假设

本研究旨在确定所有影响原发性压力性尿失禁(SUI)患者对尿道周围填充注射疗法(PBI)或中段尿道吊带术(MUS)手术偏好的治疗决策因素。其次,我们探讨了患者对SUI治疗的期望,以及患者是否会将PBI视为主要治疗选择。

方法

采用定性设计,对20名原发性SUI女性患者进行了半结构化面对面访谈。排除标准为:既往接受过PBI或MUS手术;以尿急为主。访谈由三个开放式问题和一个主题列表引导。详细描述了PBI治疗和MUS手术,并分别指出其有效率为70%和90%。当连续三次访谈未发现新的治疗决策因素时,达到数据饱和。访谈进行录音并全文转录。由两名研究人员独立进行编码过程的主题分析。

结果

确定了16个程序、个人、专业、社会和外部治疗决策因素。关于对SUI治疗的期望,女性认为“不再漏尿”是一厢情愿。大多数患者接受治疗后仍有轻度持续性尿失禁。无论治疗偏好如何,患者均表示应告知女性PBI作为主要治疗选择。

结论

原发性SUI患者愿意接受PBI作为替代治疗选择,即使与全身麻醉或脊髓麻醉下进行的MUS手术相比治愈率较低。患者表示,应告知寻求治疗的原发性SUI女性PBI作为一种治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b8c/6132683/741df5e51d52/192_2018_3644_Fig1_HTML.jpg

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