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骨质疏松性胸腰椎压缩骨折:椎体成形术与保守治疗的长期回顾性比较

Osteoporotic thoracolumbar compression fractures: long-term retrospective comparison between vertebroplasty and conservative treatment.

作者信息

Martikos Konstantinos, Greggi Tiziana, Faldini Cesare, Vommaro Francesco, Scarale Antonio

机构信息

Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy.

出版信息

Eur Spine J. 2018 Jun;27(Suppl 2):244-247. doi: 10.1007/s00586-018-5605-1. Epub 2018 Apr 19.

Abstract

PURPOSE

To compare long term clinical and radiographic outcomes in osteoporotic vertebral compression fractures of the thoracolumbar spine treated with conservative treatment and percutaneous vertebroplasty.

METHODS

The retrospective study with inclusion criteria focused on osteoporotic fractures of the thoracolumbar junction (T10-L2). Clinical outcomes were evaluated by using the VAS, Oswestry and SF36 questionnaires. Radiographic outcomes were evaluated by comparing the following sagittal parameters: body angle, sagittal index of fractured vertebral body and adjacent vertebral segments kyphosis. Complications in terms of adjacent vertebral fractures and cement leakage are reported.

RESULTS

Percutaneous vertebroplasty provided better vertebral body height restoration, but was associated with a higher incidence of adjacent fractures (20%) than conservative treatment (3.5%). This fact may explain why patients treated with percutaneous vertebroplasty had worse overall kyphotic alignment at final follow-up. Cement leakage was frequent, but always asymptomatic and generally no serious complications occurred.

CONCLUSIONS

Percutaneous vertebroplasty represents a safe treatment for osteoporotic vertebral compression fractures, although it may be associated with a higher incidence of adjacent fractures and therefore worse thoracolumbar kyphosis and long-term follow-up than conservative treatment. These slides can be retrieved under Electronic Supplementary Material.

摘要

目的

比较保守治疗和经皮椎体成形术治疗胸腰椎骨质疏松性椎体压缩骨折的长期临床和影像学结果。

方法

本回顾性研究纳入标准聚焦于胸腰段交界处(T10-L2)的骨质疏松性骨折。采用视觉模拟评分法(VAS)、Oswestry功能障碍指数和SF-36健康调查简表评估临床结果。通过比较以下矢状面参数评估影像学结果:椎体角度、骨折椎体矢状指数和相邻椎体节段后凸畸形。报告相邻椎体骨折和骨水泥渗漏方面的并发症。

结果

经皮椎体成形术能更好地恢复椎体高度,但与保守治疗(3.5%)相比,相邻骨折发生率更高(20%)。这一事实可能解释了为什么经皮椎体成形术治疗的患者在最终随访时整体后凸畸形矫正效果更差。骨水泥渗漏很常见,但通常无症状,一般未发生严重并发症。

结论

经皮椎体成形术是治疗骨质疏松性椎体压缩骨折的一种安全方法,尽管与保守治疗相比,其相邻骨折发生率可能更高,因此胸腰椎后凸畸形更严重,长期随访结果更差。这些幻灯片可在电子补充材料中获取。

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