Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.
Macromol Rapid Commun. 2018 May;39(10):e1800128. doi: 10.1002/marc.201800128. Epub 2018 Apr 20.
Degradable shape memory polymers (SMPs), especially for polyurethane-based SMPs, have shown great potential for biomedical applications. How to reasonably fabricate SMPs with the ideal combination of degradability, shape reconfigurability, and reprocessability is a critical issue and remains a challenge for medical disposable materials. Herein, a shape memory poly(urethane-urea) with synergetic triple dynamic covalent bonds is reported via embedding polycaprolactone unit into poly(urethane-urea) with the hindered urea dynamic bond. The single polymer network is biodegradable, thermadapt, and reprocessable, without sacrificing the outstanding shape memory performance. Such a shape memory network with plasticity and reprocessability is expected to have significant and positive impact on the medical device industry.
可降解形状记忆聚合物（SMPs），特别是基于聚氨酯的 SMPs，在生物医学应用中显示出巨大的潜力。如何合理地制造具有可降解性、形状可重构性和可再加工性的理想组合的 SMPs 是一个关键问题，也是医用一次性材料面临的挑战。本文通过将聚己内酯单元嵌入具有受阻脲基动态键的聚（氨酯-脲）中，报道了一种协同三重动态共价键的形状记忆聚（氨酯-脲）。该单聚合物网络具有生物降解性、热适应性和可再加工性，同时不牺牲优异的形状记忆性能。这种具有塑性和可再加工性的形状记忆网络有望对医疗器械行业产生重大而积极的影响。
