Gomes P, Cassanas G, Halberg F, Hermida R, Robel P, Baulieu E E, Lakatua D, Haus E
I.N.S.E.R.M., U. 33, Lab. Hormones, Bicêtre.
C R Acad Sci III. 1988;306(7):261-4.
In North American women at low or high risk of developing breast cancer, as assessed by an epidemiologic questionnaire, the plasma concentration of dehydroepiandrosterone sulfate shows a statistically significant circannual variation. In adolescents, in all seasons, circulating dehydroepiandrosterone sulfate is a classifier of the risk of developing breast cancer, a relatively low concentration of this hormone being associated with an increased risk.