转导技术问世——可视化染色体之间的增强子-启动子通讯。
Transvection Goes Live-Visualizing Enhancer-Promoter Communication between Chromosomes.
机构信息
Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York, USA; Janelia Research Campus of the HHMI, Ashburn, Virginia, USA.
出版信息
Mol Cell. 2018 Apr 19;70(2):195-196. doi: 10.1016/j.molcel.2018.04.004.
Lim et al. (2018) use live imaging in Drosophila embryos to show that enhancers can drive transcription from promoters on another chromosome when they are in close proximity. In addition, they show that multiple promoters can access the same enhancer without competition, potentially sharing a pool of factors in a transcriptional "hub."
林等人（2018）利用活体成像在果蝇胚胎中表明，当增强子时与另一条染色体上的启动子接近时，它们可以驱动转录。此外，他们还表明，多个启动子可以在没有竞争的情况下访问相同的增强子，从而在转录“枢纽”中潜在地共享因子池。
Zotero 插件