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Imaging of DNA and RNA in Living Eukaryotic Cells to Reveal Spatiotemporal Dynamics of Gene Expression.
Annu Rev Biochem. 2020 Jun 20;89:159-187. doi: 10.1146/annurev-biochem-011520-104955. Epub 2020 Mar 16.
2
Genome organization in the nucleus: From dynamic measurements to a functional model.
Methods. 2017 Jul 1;123:128-137. doi: 10.1016/j.ymeth.2017.01.008. Epub 2017 Feb 1.
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Tethering RNA to chromatin for fluorescence microscopy based analysis of nuclear organization.
Methods. 2017 Jul 1;123:89-101. doi: 10.1016/j.ymeth.2017.01.010. Epub 2017 Feb 14.
5
From snapshots to moving pictures: new perspectives on nuclear organization.
Trends Cell Biol. 2001 Dec;11(12):519-25. doi: 10.1016/s0962-8924(01)02174-2.
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Principles of nuclear organization.
Cell Biol Int Rep. 1990 Dec;14(12):1051-74. doi: 10.1016/0309-1651(90)90014-p.
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[Imaging of mRNA nuclear export in a living cell].
Tanpakushitsu Kakusan Koso. 2003 Mar;48(4 Suppl):421-9.
8
Temporal and spatial regulation of mRNA export: Single particle RNA-imaging provides new tools and insights.
Bioessays. 2017 Feb;39(2). doi: 10.1002/bies.201600124. Epub 2017 Jan 4.
9
Visualizing chromatin dynamics in interphase nuclei.
Science. 2002 May 24;296(5572):1412-6. doi: 10.1126/science.1067703.
10
Imaging single mRNAs to study dynamics of mRNA export in the yeast Saccharomyces cerevisiae.
Methods. 2016 Apr 1;98:104-114. doi: 10.1016/j.ymeth.2016.01.006. Epub 2016 Jan 16.

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High-resolution dynamic imaging of chromatin DNA communication using Oligo-LiveFISH.
Cell. 2025 Jun 12;188(12):3310-3328.e27. doi: 10.1016/j.cell.2025.03.032. Epub 2025 Apr 15.
3
Epigenetic modifications involving ncRNAs in digestive system cancers: focus on histone modification.
Clin Epigenetics. 2024 Nov 19;16(1):162. doi: 10.1186/s13148-024-01773-0.
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Molecular Spies in Action: Genetically Encoded Fluorescent Biosensors Light up Cellular Signals.
Chem Rev. 2024 Nov 27;124(22):12573-12660. doi: 10.1021/acs.chemrev.4c00293. Epub 2024 Nov 13.
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Optogenetic dissection of transcriptional repression in a multicellular organism.
Nat Commun. 2024 Oct 26;15(1):9263. doi: 10.1038/s41467-024-53539-0.
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MONITTR allows real-time imaging of transcription and endogenous proteins in C. elegans.
J Cell Biol. 2025 Jan 6;224(1). doi: 10.1083/jcb.202403198. Epub 2024 Oct 14.
8
Approaches to probe and perturb long noncoding RNA functions in diseases.
Curr Opin Genet Dev. 2024 Apr;85:102158. doi: 10.1016/j.gde.2024.102158. Epub 2024 Feb 26.
9
Real-time single-molecule imaging of transcriptional regulatory networks in living cells.
Nat Rev Genet. 2024 Apr;25(4):272-285. doi: 10.1038/s41576-023-00684-9. Epub 2024 Jan 9.
10
Translation Dynamics of Single mRNAs in Live Cells.
Annu Rev Biophys. 2024 Jul;53(1):65-85. doi: 10.1146/annurev-biophys-030822-034116. Epub 2024 Jun 28.

本文引用的文献

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The Control Centers of Biomolecular Phase Separation: How Membrane Surfaces, PTMs, and Active Processes Regulate Condensation.
Mol Cell. 2019 Oct 17;76(2):295-305. doi: 10.1016/j.molcel.2019.09.016. Epub 2019 Oct 8.
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Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences.
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Fast objective coupled planar illumination microscopy.
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Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging.
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Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs.
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RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether.
Cell. 2019 Sep 19;179(1):147-164.e20. doi: 10.1016/j.cell.2019.08.050.
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Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF.
Mol Cell. 2019 Nov 7;76(3):395-411.e13. doi: 10.1016/j.molcel.2019.07.039. Epub 2019 Sep 12.
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CRISPR/dual-FRET molecular beacon for sensitive live-cell imaging of non-repetitive genomic loci.
Nucleic Acids Res. 2019 Nov 18;47(20):e131. doi: 10.1093/nar/gkz752.
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CRISPR-mediated live imaging of genome editing and transcription.
Science. 2019 Sep 20;365(6459):1301-1305. doi: 10.1126/science.aax7852. Epub 2019 Sep 5.
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Live imaging of mRNA using RNA-stabilized fluorogenic proteins.
Nat Methods. 2019 Sep;16(9):862-865. doi: 10.1038/s41592-019-0531-7. Epub 2019 Aug 30.

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