Department of Otorhinolaryngology-Head and Neck Surgery, Fu Jen Catholic University Hospital, New Taipei, Taiwan; Voice Center, Department of Otolaryngology, Cheng Hsin General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan.
Voice Center, Department of Otolaryngology, Cheng Hsin General Hospital, Taipei, Taiwan.
J Voice. 2019 Sep;33(5):747-750. doi: 10.1016/j.jvoice.2018.03.012. Epub 2018 Apr 17.
We sought to determine the outcomes of office-based autologous fat injection laryngoplasty in the treatment of patients under 50 years old with glottic insufficiency but without neurological problems or acquired organic lesions in the vocal fold.
We conducted a retrospective chart review of consecutive patients under 50 years of age who underwent office-based autologous fat injection laryngoplasty for glottic insufficiency. None of the patients presented neurological problems or acquired organic lesions in the vocal fold. Videolaryngostroboscopic data, objective voice assessment, perceptual measurements of vocal quality, and subjective ratings of voice quality were evaluated before and after treatment.
The 23 patients (7 men and 16 women) in this study presented significant improvements in phonatory function in terms of maximum phonation time, jitter, grade, asthenia, and Voice Handicap Index-10 (VHI-10) values at 3 months. Significant improvements in terms of jitter, noise-to-harmonic ratio, grade, roughness, breathiness, asthenia, and the VHI-10 values were also observed at 6 months.
Glottic insufficiency in younger patients without neurological problems or acquired organic lesions in the vocal fold can be treated effectively using office-based autologous fat injection laryngoplasty. Significant improvements in phonatory function were observed even 6 months after surgery.
我们旨在探讨在无神经问题或声带获得性器质性病变的前提下，50 岁以下声门闭合不全患者行局麻下自体脂肪注射喉成形术的治疗效果。
我们对连续接受局麻下自体脂肪注射喉成形术治疗声门闭合不全的 50 岁以下患者进行回顾性病历分析。这些患者均无神经问题或声带获得性器质性病变。在治疗前后，我们评估了频闪喉镜、客观嗓音评估、嗓音质量的感知测量和嗓音质量的主观评分。
23 例患者（7 名男性，16 名女性）在最长发声时间、基频微扰、噪声能量、嘶哑、嗓音障碍指数 10 （VHI-10）值方面的发音功能得到显著改善，且改善情况在术后 3 个月即可观察到。在基频微扰、噪声能量与谐噪比、嘶哑、粗糙声、气息声、无力和 VHI-10 值方面，患者的改善情况在术后 6 个月时仍可观察到。
局麻下自体脂肪注射喉成形术可有效治疗无神经问题或声带获得性器质性病变的年轻声门闭合不全患者。即使在术后 6 个月，患者的发音功能也能得到显著改善。
