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半面痉挛中的血管冲突:文献综述及解剖学-外科学意义

The conflicting vessels in hemifacial spasm: Literature review and anatomical-surgical implications.

作者信息

Mercier P, Sindou M

机构信息

Department of anatomy, faculté de santé, 28, rue Roger-Amsler, CS 74521, 49045 Angers cedex 1, France.

University Lyon 1, Domaine-Rockefeller, 69000 Lyon, France; Groupe ELSAN, clinique Bretéché, Nantes, France.

出版信息

Neurochirurgie. 2018 May;64(2):94-100. doi: 10.1016/j.neuchi.2018.01.004. Epub 2018 Apr 19.

Abstract

Since several decades, it has been established that so-called primary hemifacial spasm is linked to neuro-vascular conflicts in the facial nerve, especially its root exit zone (REZ). Based on our review of the detailed publications of literature (2489 patients), together with our own series (340 patients), the responsible vessels found at surgery were: the posterior inferior cerebellar artery in 47.2%, the anterior inferior cerebellar artery in 45.9%, the vertebro-basilar artery in 17.5%, another (smaller) artery in 11.7%. Participation of veins was very diversely estimated according to series: 4.9% on average. Multiple neuro-vascular conflicts in a same individual were frequently observed, in the order of 20 to 30% according to authors, 37% in our series. Also, abnormal conformation of the posterior fossa may play a role, such as flatness of the posterior fossa or exiguity of the cerebello-pontine angle cistern. Whatever, most neurovascular conflicts are located at brainstem and/or ventrocaudally to the facial REZ, in the order of 95% of the patients. The anatomical location and conformation of the compressive vessel(s) are crucial in determining the difficulties to identify the responsible conflict(s) and to perform effective and safe decompression. Main difficulties are encountered in cases with arteriosclerotic megadolicho-vertebrobasilar artery, at brainstem, especially when PICA and/or AICA come in association, or for neurovascular conflict(s) located at the cisternal or the intrameatal portions of the facial root. Later ones can be alone or in addition to NVC at brainstem/REZ.

摘要

几十年来,已经确定所谓的原发性面肌痉挛与面神经中的神经血管冲突有关,尤其是其神经根出口区(REZ)。基于我们对详细文献出版物(2489例患者)以及我们自己的系列病例(340例患者)的回顾,手术中发现的责任血管如下:小脑后下动脉占47.2%,小脑前下动脉占45.9%,椎基底动脉占17.5%,另一(较小)动脉占11.7%。根据不同系列,静脉参与情况的估计差异很大:平均为4.9%。同一患者中经常观察到多个神经血管冲突,根据作者的报告,发生率在20%至30%之间,在我们的系列中为37%。此外,后颅窝的异常形态可能起作用,例如后颅窝扁平或桥小脑角池狭小。无论如何,大多数神经血管冲突位于脑干和/或面神经REZ的腹侧尾端,约占患者的95%。压迫血管的解剖位置和形态对于确定识别责任冲突以及进行有效和安全减压的难度至关重要。在患有动脉硬化性巨长椎基底动脉的病例中,在脑干处,特别是当小脑后下动脉和/或小脑前下动脉合并出现时,或者对于位于面神经根部脑池或管内部分的神经血管冲突,会遇到主要困难。后者可以单独出现,也可以是除脑干/REZ处的神经血管冲突之外的情况。

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