迷走神经刺激疗法后癫痫发作和癫痫持续状态加重：首例儿科病例及文献综述
Aggravation of seizures and status epilepticus after vagal nerve stimulation therapy: the first pediatric case and review of the literature.
作者信息
Arhan Ebru, Serdaroğlu Ayşe, Hirfanoğlu Tuğba, Kurt Gökhan
机构信息
Department of Pediatric Neurology, Gazi University School of Medicine, Ankara, Turkey.
Pediatric Neurology Department, Gazi University Faculty of Medicine, 10 th Floor Besevler-, Ankara, Turkey.
出版信息
Childs Nerv Syst. 2018 Sep;34(9):1799-1801. doi: 10.1007/s00381-018-3806-x. Epub 2018 Apr 22.
BACKGROUND
We describe the first child with drug-resistant epilepsy in whom vagus nerve stimulation aggravated seizures and emerged status epilepticus after the increase in vagal nerve stimulation current output.
OBJECTIVE
A 13-year-old girl presented with refractory secondary generalized focal epilepsy. Vagal nerve stimulator was implanted because of drug-resistant epilepsy. After the increase of vagal nerve stimulator current output to a relatively high level, the patient experienced seizure aggravation and status epilepticus.
CONCLUSION
We conclude that vagus nerve stimulation may induce paradoxical seizures and may lead to status epilepticus, similarly to some antiepileptic drugs.
背景
我们描述了首例耐药性癫痫患儿，其迷走神经刺激在迷走神经刺激电流输出增加后加重了癫痫发作并出现癫痫持续状态。
目的
一名13岁女孩患有难治性继发性全身性局灶性癫痫。因耐药性癫痫植入了迷走神经刺激器。在将迷走神经刺激器电流输出增加到相对较高水平后，患者癫痫发作加重并出现癫痫持续状态。
结论
我们得出结论，迷走神经刺激可能诱发反常性癫痫发作，并可能导致癫痫持续状态，这与某些抗癫痫药物类似。
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