Haidarliu Sebastian, Ahissar Ehud, Saraf-Sinik Inbar
Department of Neurobiology, The Weizmann Institute of Science, Rehovot, 76100, Israel.
J Physiol Sci. 2018 Nov;68(6):875-880. doi: 10.1007/s12576-018-0613-9. Epub 2018 Apr 21.
A self-adjusting head holder is designed to allow stable fixation and precise positioning (anterior-posterior, pitch, and roll) of guinea pig head in stereotaxic devices. These are achieved with no use of ear-bars. It is thus easy to use, preferable for studies of the auditory system, and for avoiding tissue damage of the ear in general. This head holder can accommodate various head sizes and is thus adapted for males and females of a large range of body weights, as confirmed for guinea pigs of 360-940 g. Moreover, this head holder is easy and cost-effective to manufacture, making it accessible for any lab. Here, we present background and mechanical rationale, the technical specifications, and step-by-step manufacturing instructions for the stainless-steel and the plastic MRI-compatible versions of our self-adjusting head holder.
一种自调节头架旨在实现豚鼠头部在立体定位装置中的稳定固定和精确放置（前后、俯仰和滚动）。这些功能无需使用耳杆即可实现。因此，它易于使用，对于听觉系统研究以及一般情况下避免耳部组织损伤来说是更可取的。这种头架可以适应各种头型大小，因此适用于体重范围较大的雄性和雌性豚鼠，体重在360 - 940克的豚鼠已得到证实。此外，这种头架易于制造且成本效益高，任何实验室都可以使用。在此，我们介绍了背景和机械原理、技术规格，以及我们自调节头架的不锈钢和塑料MRI兼容版本的分步制造说明。
