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一种用于研究猪中枢神经结构的立体定位仪。

A stereotaxic apparatus for the study of the central nervous structures in the pig.

作者信息

Marcilloux J C, Rampin O, Felix M B, Laplace J P, Albe-Fessard D

机构信息

Unité de Neurobiologie des régulations nutritionnelles, Station de Physiologie de la Nutrition, I.N.R.A., Jouy en Josas, France.

出版信息

Brain Res Bull. 1989 Mar;22(3):591-7. doi: 10.1016/0361-9230(89)90118-4.

DOI:10.1016/0361-9230(89)90118-4
PMID:2653572
Abstract

An apparatus has been developed derived from the Horsley-Clarke principle. Specific requirement was to use large breeds of pigs from weaning to adult age (5 to 120 kg). The pig auditory canals are oblique; the measurement of the corresponding angles was achieved by means of two interconnected barrels, used afterwards to fix the ear-bars. The wide variability of the skull morphology led to the systematic use of ventriculography with a liquid of contrast. Consequently the pieces allowing the head fixation in the stereotaxic apparatus were designed to avoid any shadow on the brain area. As it was not always possible to localize the commissura anterior, the anterior border of the recessus preopticus was chosen to determine, together with the commissura posterior, the reference horizontal plane. The antero-posterior coordinates were counted from the anterior border of the commissura posterior. The methodology, which has been tested in a wide range of pigs, is discussed in relation with the methods used for other animal species.

摘要

一种基于霍斯利-克拉克原理开发的仪器。具体要求是使用从断奶到成年(5至120千克)的大型猪种。猪的耳道是倾斜的;通过两个相互连接的圆筒测量相应角度,之后用于固定耳杆。颅骨形态的广泛变异性导致系统地使用造影剂进行脑室造影。因此,立体定向仪中用于固定头部的部件被设计成避免在脑区产生任何阴影。由于并非总能定位前连合,因此选择视前隐窝的前缘与后连合一起确定参考水平面。前后坐标从后连合的前缘开始计数。本文讨论了在多种猪身上测试过的该方法,并与其他动物物种所使用的方法进行了比较。

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