从沙漠陆龟呼吸道分离出的BH29菌株的高质量基因组草图序列。

Weitzman Chava L, Tillett Richard L, Sandmeier Franziska C, Tracy C Richard, Alvarez-Ponce David

1Biology Department, University of Nevada, Reno, USA.

2Nevada Center for Bioinformatics, University of Nevada, Reno, USA.

Stand Genomic Sci. 2018 Apr 11;13:9. doi: 10.1186/s40793-018-0309-z. eCollection 2018.

is one of the pathogens that can cause upper respiratory tract disease in desert tortoises, . We sequenced the genome of BH29 (ATCC 700618 = MCCM 03231), isolated from the upper respiratory tract of a Mojave desert tortoise with upper respiratory tract disease. The sequenced draft genome, organized in 25 scaffolds, has a length of 960,895 bp and a G + C content of 27.54%. A total of 788 protein-coding sequences, six pseudogenes and 35 RNA genes were identified. The potential presence of cytadhesin-encoding genes is investigated. This genome will enable comparative genomic studies to help understand the molecular bases of the pathogenicity of this and other species.

是可导致沙漠陆龟上呼吸道疾病的病原体之一。我们对从一只患有上呼吸道疾病的莫哈韦沙漠陆龟的上呼吸道分离出的BH29（ATCC 700618 = MCCM 03231）的基因组进行了测序。测序的草图基因组由25个支架组成，长度为960,895 bp，G + C含量为27.54%。共鉴定出788个蛋白质编码序列、6个假基因和35个RNA基因。研究了编码细胞粘附素基因的潜在存在情况。该基因组将有助于进行比较基因组研究，以帮助了解该物种和其他物种致病性的分子基础。