对于一名晚期多灶性基底细胞癌患者， upfront放疗联合同时期及辅助维莫德吉治疗有效且耐受性良好。
Upfront Radiotherapy with Concurrent and Adjuvant Vismodegib Is Effective and Well-Tolerated in a Patient with Advanced, Multifocal Basal Cell Carcinoma.
作者信息
Franco Abigail I, Eastwick Gary, Farah Ramsay, Heyboer Marvin, Lee Mijung, Aridgides Paul
机构信息
St. Joseph's Hospital Health Center, 301 Prospect Avenue, Syracuse, NY 13203, USA.
Upstate University Hospital, 750 E. Adams Street, Syracuse, NY 13210, USA.
出版信息
Case Rep Dermatol Med. 2018 Feb 21;2018:2354146. doi: 10.1155/2018/2354146. eCollection 2018.
We present a case report of a male with multifocal and extensive basal cell carcinoma. Due to extremely large size and deep tumor infiltration, he was not a surgical candidate. Combined modality treatment of fractionated radiation with concurrent vismodegib was chosen. Concurrent treatment was previously reported in the and setting. This is the first case of concurrent vismodegib and radiation therapy for management. The patient experienced complete response in all treated lesions.
我们报告一例患有多灶性广泛性基底细胞癌的男性病例。由于肿瘤尺寸极大且浸润较深，他不适合手术治疗。因此选择了分次放疗联合维莫德吉同步治疗的综合治疗方案。同步治疗此前曾在[具体情况1]和[具体情况2]中报道过。这是首例采用维莫德吉与放射治疗同步进行基底细胞癌治疗的病例。该患者所有接受治疗的病灶均实现了完全缓解。
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