Sigwart U, Kaufmann U, Goy J J, Grbic M, Golf S, Essinger A, Fischer A, Sadeghi H, Mirkovitch V, Kappenberger L
Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Eur Heart J. 1988 Mar;9 Suppl C:31-7. doi: 10.1093/eurheartj/9.suppl_c.31.
Balloon angioplasty fails to provide acceptable long-term results for a significant proportion of patients. An intravascular mechanical support, developed with the aim of preventing restenosis and acute closure of diseased arteries after transluminal angioplasty, was implanted in 44 patients (39 male and five female), aged from 35 to 70 years (mean 56 years) with documented restenosis of native coronary artery (41 stents) and bypass grafts (12 stents). In the group of bypass graft patients there was no local restenosis and no major complication. In patients in whom stents were placed in native coronary arteries, the complication rate was higher (two patients died after coronary bypass surgery). One patient died suddenly at home. Except for one patient, in whom a new lesion developed proximally with extension into the stent, no case of restenosis could be observed. Despite the still relatively high complication rate, we feel that stenting may present a rational approach to the unresolved problem of restenosis after coronary angioplasty.
对于相当一部分患者而言，球囊血管成形术无法提供令人满意的长期效果。一种旨在预防经腔血管成形术后病变动脉再狭窄和急性闭塞而研发的血管内机械支撑装置，被植入了44例患者（39例男性和5例女性）体内，这些患者年龄在35至70岁之间（平均56岁），记录显示其存在自身冠状动脉（41个支架）和旁路移植物（12个支架）再狭窄情况。在旁路移植物患者组中，未出现局部再狭窄且无重大并发症。在自身冠状动脉植入支架的患者中，并发症发生率更高（2例患者在冠状动脉搭桥手术后死亡）。1例患者在家中突然死亡。除1例患者在支架近端出现新病变并延伸至支架内，未观察到再狭窄病例。尽管并发症发生率仍然相对较高，但我们认为支架置入术可能是解决冠状动脉血管成形术后再狭窄这一未解决问题的合理方法。
