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探索 PTSD 中分离亚型的证据:分离者的基线症状结构、病因和治疗效果。

Exploring evidence of a dissociative subtype in PTSD: Baseline symptom structure, etiology, and treatment efficacy for those who dissociate.

机构信息

Department of Psychological Sciences.

Department of Psychology, University of Washington.

出版信息

J Consult Clin Psychol. 2018 May;86(5):439-451. doi: 10.1037/ccp0000297.

Abstract

OBJECTIVE

With the inclusion of a dissociative subtype, recent changes to the DSM-5 diagnosis of posttraumatic stress disorder (PTSD) have emphasized the role of dissociation in the experience and treatment of the disorder. However, there is a lack of research exploring the clinical impact for highly dissociative groups receiving treatment for PTSD. The current study examined the presence and clinical impact of a dissociative subtype in a sample of individuals receiving treatment for chronic PTSD.

METHOD

This study used latent transition analyses (LTA), an expanded form of latent profile analyses (LPA), to examine latent profiles of PTSD and dissociation symptoms before and after treatment for individuals (N = 200) receiving prolonged exposure (PE) or sertraline treatment for chronic PTSD.

RESULTS

The best fitting LTA model was one with a 4-class solution at both pretreatment and posttreatment. There was a latent class at pretreatment with higher levels of dissociative symptoms. However, this class was also marked by higher reexperiencing symptoms, and membership was not predicted by chronic child abuse. Further, although those in the class were less likely to transition to the responder class overall, this was not the case for exposure-based treatment specifically.

CONCLUSION

These findings are not in line with the dissociative-subtype theoretical literature that proposes those who dissociate represent a clinically distinct group that may respond worse to exposure-based treatments for PTSD. (PsycINFO Database Record

摘要

目的

随着 DSM-5 创伤后应激障碍(PTSD)诊断标准的变化,包括分离亚型,突显了分离在该障碍的经历和治疗中的作用。然而,缺乏研究探索接受 PTSD 治疗的高度分离群体的临床影响。本研究调查了接受慢性 PTSD 治疗的个体样本中分离亚组的存在及其对临床的影响。

方法

本研究使用潜在转变分析(LTA),即潜在剖面分析(LPA)的扩展形式,来检查接受延长暴露(PE)或舍曲林治疗的个体(N=200)在 PTSD 和分离症状治疗前后的潜在模式。

结果

最适合的 LTA 模型在治疗前和治疗后均为 4 类解决方案。在治疗前有一个具有更高分离症状水平的潜在类别。然而,这个类别也以更高的再体验症状为特征,且慢性儿童虐待并不能预测其成员身份。此外,尽管该类别中的个体总体上不太可能向应答者类别转变,但这在基于暴露的治疗中并非如此。

结论

这些发现与分离亚型理论文献不一致,该文献提出,那些有分离的人代表一个临床上不同的群体,他们可能对 PTSD 的基于暴露的治疗反应更差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa28/5918299/9fe8e968ca66/nihms943026f1.jpg

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