Nagasaka T, Hirata K, Nunomura T
Department of Physiology, School of Medicine, Kanazawa University, Japan.
Jpn J Physiol. 1988;38(1):67-75. doi: 10.2170/jjphysiol.38.67.
We compared the responses of finger blood flow to local and/or whole body warming, as measured by laser Doppler flowmetry (PERIFLUX PF-1d) (LDF), and by venous occlusion plethysmography (BF). The subject's hands were immersed in a bath of water whose temperature (Tw) was initially set at 25 degrees C. The tested hand was kept at about 10 cm above heart level to facilitate the drainage of finger veins during measurement. The ambient temperature (Ta) was initially 20 degrees C. Then, measurements were made under the following conditions on separate days: 1) local hand warming only (LHW), Tw raised from 25 to 40 degrees C; 2) whole body warming only (WBW), Ta was raised from 20 to 35 degrees C; and 3) LHW and WBW combined (CW), LHW (Tw was raised to 35 degrees C and maintained) was followed by WBW. Results showed that both LHW and WBW increased LDF and BF. LDF signals correlated significantly with BF values in each condition (r = 0.932-0.955). However, the slope of the line showing the relationship of LDF and BF, determined by least squares linear regression analysis, was steeper in LHW than in WBW. In CW, the slope showed a bend, creating two different sections in the relationship. Below the bend the relation was steeper and showed a similar slope as that in LHW; above the bend, the relation was more gradual and a similar slope as that in WBW. No such bend was observed in measurements of the forearm skin in CW.(ABSTRACT TRUNCATED AT 250 WORDS)
我们比较了通过激光多普勒血流仪（PERIFLUX PF-1d）（LDF）和静脉阻断体积描记法（BF）测量的手指血流对局部和/或全身升温的反应。受试者的双手浸入水温（Tw）初始设定为25摄氏度的水浴中。测试手保持在心脏水平上方约10厘米处，以便在测量期间促进手指静脉的引流。环境温度（Ta）初始为20摄氏度。然后，在不同的日子里在以下条件下进行测量：1）仅局部手部升温（LHW），Tw从25摄氏度升至40摄氏度；2）仅全身升温（WBW），Ta从20摄氏度升至35摄氏度；3）LHW和WBW联合（CW），先进行LHW（Tw升至35摄氏度并保持），然后进行WBW。结果表明，LHW和WBW均增加了LDF和BF。在每种条件下，LDF信号与BF值显著相关（r = 0.932 - 0.955）。然而，通过最小二乘线性回归分析确定的显示LDF与BF关系的直线斜率，LHW中比WBW中更陡。在CW中，斜率出现弯曲，在关系中形成两个不同的部分。在弯曲点以下，关系更陡，显示出与LHW中相似的斜率；在弯曲点以上，关系更平缓，显示出与WBW中相似的斜率。在CW中测量前臂皮肤时未观察到这种弯曲。（摘要截断于250字）
