Messing B, Landais P, Goldfarb B, Lemann M, Joyeux H, Gouttebel M C, Robert D, Bouletreau P, Matuchansky C, Beau P
Hôpital Saint-Lazare, Paris.
Presse Med. 1988 May 7;17(17):845-9.
Home parenteral nutrition (HPN) is a growing therapy in North America and Europe. This first multicenter retrospective study of HPN in France has collected data on 81 patients sent home before December 31st, 1985. Intestinal failure, secondary to short bowel syndrome, small bowel stenosis or fistula, was the main indication for HPN. In 95 p. 100 of the cases, the clinical nutritional status during HPN was either normal or subnormal. The annual incidence of catheter change for technical complication was 0.78 and the mortality rate was 1.2 p. 100. Social rehabilitation was recovered during HPN in 60 p. 100 of patients. Thirty percent of the patients died of their primary disease during HPN but 43 p. 100 were off treatment, and 27 p. 100 were on HPN at the end of the study. The cost of HPN was reduced by 64 p. 100 in comparison with the cost of parenteral nutrition carried out in hospital.
家庭肠内营养(HPN)在北美和欧洲是一种日益普及的治疗方法。法国这项关于HPN的首个多中心回顾性研究收集了1985年12月31日前回家的81例患者的数据。继发于短肠综合征、小肠狭窄或瘘管的肠衰竭是HPN的主要适应症。在95%的病例中,HPN期间的临床营养状况正常或低于正常水平。因技术并发症而更换导管的年发生率为0.78,死亡率为1.2%。60%的患者在HPN期间恢复了社会康复。30%的患者在HPN期间死于原发性疾病,但43%的患者停止了治疗,27%的患者在研究结束时仍在接受HPN治疗。与在医院进行的肠内营养费用相比,HPN的费用降低了64%。