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基于习惯的干预措施在超重和肥胖成年人中的体重维持:一项随机对照试验。

Habit-based interventions for weight loss maintenance in adults with overweight and obesity: a randomized controlled trial.

机构信息

Faculty of Health Sciences and Medicine, Bond University, Gold Coast, QLD, Australia.

Centre for Research in Evidence-Based Practice (CREBP), Bond University, Gold Coast, QLD, Australia.

出版信息

Int J Obes (Lond). 2019 Feb;43(2):374-383. doi: 10.1038/s41366-018-0067-4. Epub 2018 Apr 23.

Abstract

OBJECTIVES

The objective of this study was to determine whether habit-based interventions are clinically beneficial in achieving long-term (12-month) weight loss maintenance and explore whether making new habits or breaking old habits is more effective.

METHODS

Volunteer community members aged 18-75 years who had overweight or obesity (BMI ≥ 25 kg/m) were randomized in a single-blind, three-arm, randomized controlled trial. Ten Top Tips (TTT), Do Something Different (DSD), and the attention-only waitlist (WL) control groups were conducted for 12 weeks from July to October 2015. Participants were followed up post-intervention (all groups) and at 6 and 12-month post-intervention (Ten Top Tips and Do Something Different only). The primary outcome was weight-loss maintenance at 12-month follow-up. Secondary outcomes included weight loss at all time points, fruit and vegetable consumption, exercise, wellbeing, depression, anxiety, habit strength, and openness to change.

RESULTS

Of the 130 participants assessed for eligibility, 75 adults (mean BMI 34.5 kg/m [SD 6.2]), with a mean age of 51 years were recruited. Assessments were completed post-intervention by 66/75 (88%) of participants and by 43/50 (86%) at 12 months. At post-intervention, participants in the Ten Top Tips (-3.3 kg; 95% CI -5.2, -1.4) and Do Something Different (-2.9 kg; 95% CI -4.3, -1.4) interventions lost significantly more weight (P = < .001) than those on the waitlist control (-0.4 kg; 95% CI -1.2, 0.3). Both intervention groups continued to lose further weight to the 12-month follow-up; TTT lost an additional -2.4 kg (95% CI -5.1, 0.4) and DSD lost -1.7 kg (95% CI -3.4, -0.1). At 12-month post-intervention, 28/43 (65%) of participants in both intervention groups had reduced their total body weight by ≥5%, a clinically important change.

CONCLUSIONS

Habit-based weight-loss interventions-forming new habits (TTT) and breaking old habits (DSD), resulted in clinically important weight-loss maintenance at 12-month follow-up.

摘要

目的

本研究旨在确定基于习惯的干预措施是否在实现长期(12 个月)体重维持方面具有临床益处,并探讨形成新习惯和打破旧习惯哪个更有效。

方法

2015 年 7 月至 10 月,招募了年龄在 18-75 岁之间、超重或肥胖(BMI≥25kg/m2)的社区志愿者,采用单盲、三臂、随机对照试验进行分组。10 个最佳提示(TTT)、做不同的事情(DSD)和仅关注等待名单(WL)对照组分别进行 12 周。所有组均在干预后进行随访,并在干预后 6 个月和 12 个月时(仅 TTT 和 DSD 组)进行随访。主要结局是 12 个月时的体重维持情况。次要结局包括所有时间点的体重减轻、水果和蔬菜摄入量、运动、幸福感、抑郁、焦虑、习惯强度和改变的开放性。

结果

在评估合格的 130 名参与者中,有 75 名成年人(平均 BMI 34.5kg/m2[SD 6.2]),平均年龄为 51 岁,符合入选标准。在干预后,66/75(88%)名参与者完成了评估,在 12 个月时,43/50(86%)名参与者完成了评估。在干预后,TTT(-3.3kg;95%CI-5.2,-1.4)和 DSD(-2.9kg;95%CI-4.3,-1.4)干预组的参与者体重明显减轻(P<0.001),而等待名单对照组(-0.4kg;95%CI-1.2,0.3)体重减轻。两组干预组在 12 个月的随访中继续减轻体重;TTT 进一步减轻了-2.4kg(95%CI-5.1,0.4),DSD 减轻了-1.7kg(95%CI-3.4,-0.1)。在干预后 12 个月时,TTT 和 DSD 两个干预组中有 28/43(65%)名参与者的总体体重减轻≥5%,这是一个具有临床意义的变化。

结论

基于习惯的减肥干预措施——形成新习惯(TTT)和打破旧习惯(DSD),在 12 个月的随访中导致了具有临床意义的体重维持。

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