Koolwal Juhi, Birkemeier Krista L, Zreik Riyam T, Mattix Kelly D
Texas A&M Health Science Center College of Medicine, Temple, Texas.
Department of Radiology, Baylor Scott & White McLane Children's Medical Center, Texas A&M University Health Sciences, Temple, Texas.
Proc (Bayl Univ Med Cent). 2018 Jan 11;31(1):97-99. doi: 10.1080/08998280.2017.1401845. eCollection 2018 Jan.
Focal nodular hyperplasia (FNH) is a benign hepatic tumor rarely seen in pediatric patients, with most cases reported in school-aged children with a history of malignancy, liver disease, chemotherapy, or hematopoietic stem cell therapy. Despite having advanced radiographic imaging, diagnosing FNH before surgical resection can be difficult. We report a rare case of pedunculated FNH presenting as a large abdominal mass palpated on physical exam in a healthy 3-year-old girl with no history of malignancy or underlying liver disease. Ultrasound, computed tomography, and magnetic resonance imaging (MRI) did not demonstrate the typical imaging characteristics of FNH, because the mass was pedunculated with a poorly visualized central scar. Because approximately 75% of all primary hepatic tumors in this age group are malignant, this report also discusses the importance of adding hepatobiliary phase imaging with MRI to avoid, if possible, the need for biopsy or surgical resection of a benign hepatic tumor.
局灶性结节性增生(FNH)是一种在儿科患者中罕见的良性肝肿瘤,大多数病例报道于有恶性肿瘤、肝脏疾病、化疗或造血干细胞治疗史的学龄儿童。尽管有先进的影像学检查,但在手术切除前诊断FNH可能很困难。我们报告了一例罕见的带蒂FNH病例,该病例表现为一名健康3岁女孩体检时可触及的巨大腹部肿块,该女孩无恶性肿瘤或潜在肝脏疾病史。超声、计算机断层扫描和磁共振成像(MRI)均未显示FNH的典型影像学特征,因为肿块有蒂且中央瘢痕显示不清。由于该年龄组所有原发性肝肿瘤中约75%为恶性,本报告还讨论了在MRI检查中增加肝胆期成像的重要性,以便尽可能避免对良性肝肿瘤进行活检或手术切除。