Ramachandran Vignesh, Ding Belicia, George Rollin, Novakovic Matthew
Office of Student Affairs, School of Medicine, Baylor College of Medicine, Houston, Texas.
Department of Medicine, Baylor College of Medicine, Houston, Texas.
Proc (Bayl Univ Med Cent). 2018 Feb 1;31(1):112-114. doi: 10.1080/08998280.2017.1400874. eCollection 2018 Jan.
Serotonin syndrome (SS) is an underrecognized and potentially fatal disorder that occurs secondary to combinational use or overdose of a single serotonergic medication. The presentation may be complicated by hepatic encephalopathy in cirrhotic patients, which may also affect metabolism of these serotonergic agents. The authors report a rare case of severe SS complicated by hepatic encephalopathy secondary to cirrhosis in a 52-year-old woman after an increase in her home dosage of fluoxetine and addition of other psychiatric medications.
血清素综合征（SS）是一种未得到充分认识且可能致命的疾病，继发于单一血清素能药物的联合使用或过量使用。肝硬化患者的临床表现可能因肝性脑病而复杂化，肝性脑病也可能影响这些血清素能药物的代谢。作者报告了一例罕见的严重血清素综合征病例，该病例发生在一名52岁女性身上，她在家中增加了氟西汀剂量并加用了其他精神科药物后，继发于肝硬化并伴有肝性脑病。
