Bekele Tsegaye, Collins Evan J, Maunder Robert G, Gardner Sandra, Rueda Sergio, Globerman Jason, Le Thao Lan, Hunter Jon, Benoit Anita, Rourke Sean B, Ohtn Cohort Study Team The
The Ontario HIV Treatment Network, Toronto, ON, Canada.
Immunodeficiency Clinic, Toronto General Hospital, Toronto, ON, Canada.
AIDS Res Treat. 2018 Mar 1;2018:2187232. doi: 10.1155/2018/2187232. eCollection 2018.
We sought to estimate the prevalence of childhood adversity and examine its relationship with health outcomes among people living with HIV. Study participants included 1409 adults living with HIV and receiving care in Toronto, Canada. Data on childhood adversity, health behaviors, HIV outcome measures, depression, and health-related quality of life (HRQOL) were collected through face-to-face interviews and medical records. Statistical analyses included multivariable linear and logistic regression modeling. The prevalence of any childhood adversity was 71% (individual types ranged from 11% to 44%) and higher prevalence was associated with younger age, Indigenous or African/Caribbean/Black ethnicity, lower socioeconomic status, and higher rates of cigarette smoking and nonmedicinal drug use. Greater number of childhood adversities was associated with greater odds of depression and decreasing mental HRQOL. HIV care providers need to screen for childhood adversities and address childhood trauma within the context of HIV care.
我们试图估计儿童期逆境的患病率，并研究其与艾滋病毒感染者健康结果之间的关系。研究参与者包括1409名在加拿大多伦多接受护理的成年艾滋病毒感染者。通过面对面访谈和医疗记录收集了有关儿童期逆境、健康行为、艾滋病毒结果指标、抑郁以及健康相关生活质量（HRQOL）的数据。统计分析包括多变量线性和逻辑回归建模。任何儿童期逆境的患病率为71%（个体类型从11%到44%不等），较高的患病率与较年轻的年龄、原住民或非洲/加勒比/黑人种族、较低的社会经济地位以及较高的吸烟率和非药用药物使用率相关。儿童期逆境数量越多，抑郁几率越高，心理HRQOL越低。艾滋病毒护理提供者需要筛查儿童期逆境，并在艾滋病毒护理背景下处理儿童期创伤。
