Harding-Theobald Emily, Maraj Bharat
Department of Medicine, University of California, San Francisco Medical Center, San Francisco, CA, USA.
Case Rep Gastrointest Med. 2018 Mar 1;2018:5714053. doi: 10.1155/2018/5714053. eCollection 2018.
species colonize the human gastrointestinal tract and are rarely pathogenic. We present a case involving a cirrhotic patient who presented with sepsis and was found to have peritoneal cultures demonstrating as the sole pathogen concerning for spontaneous bacterial peritonitis. Treatment was achieved with high-dose penicillin and clindamycin but the patient developed hepatorenal syndrome and died from acute renal failure. Intra-abdominal infections are typically seen in patients undergoing peritoneal dialysis or who have recently had bowel perforation. There are few case reports of spontaneous peritonitis in patients with cirrhosis. Our case report addresses the challenges of treatment and suggests antibiotic coverage of commensal organisms in patients who do not improve with standard management.
某些物种定殖于人类胃肠道,且很少具有致病性。我们报告了一例肝硬化患者,该患者出现败血症,腹膜培养显示 为自发性细菌性腹膜炎唯一可疑的病原体。通过大剂量青霉素和克林霉素治疗取得了疗效,但患者出现了肝肾综合征并死于急性肾衰竭。腹腔内感染通常见于接受腹膜透析的患者或近期有肠穿孔的患者。肝硬化患者自发性腹膜炎的病例报告很少。我们的病例报告阐述了治疗方面的挑战,并建议对经标准治疗无改善的患者给予共生菌抗生素覆盖。