Chow Jonathan H, Galvagno Samuel M, Tanaka Kenichi A, Mazzeffi Michael A, Chancer Zackary, Henderson Reney, McCurdy Michael T
From the Department of Anesthesiology, Division of Critical Care Medicine.
Division of Cardiovascular Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland.
A A Pract. 2018 Oct 1;11(7):175-180. doi: 10.1213/XAA.0000000000000775.
Angiotensin (AT) II is an endogenous hormone that acts on venous and arterial smooth muscle to cause vasoconstriction. Recent trials have sparked great interest in its ability to be used as a vasopressor for catecholamine-refractory hypotension. Herein, we describe the successful use of AT II in a patient with a colonic perforation with septic shock refractory to conventional treatment. After AT II initiation, there was an immediate reduction in catecholamine requirement, and the patient survived.
血管紧张素（AT）II是一种内源性激素，作用于静脉和动脉平滑肌，引起血管收缩。最近的试验引发了人们对其作为去甲肾上腺素难治性低血压血管加压药的能力的极大兴趣。在此，我们描述了AT II在一名结肠穿孔伴传统治疗难治性感染性休克患者中的成功应用。开始使用AT II后，去甲肾上腺素需求量立即减少，患者存活。
