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血管紧张素 II 在难治性多系统休克中的应用:一例报告

Angiotensin II Use in Refractory Multisystem Shock: A Case Report.

作者信息

Ahmed Mohamed, Habis Saba, Mahmoud Ahmed, Rutland Cedric, Saeed Rasha

机构信息

Surgery, Riverside Community Hospital / Envision Healthcare, Riverside, USA.

Internal Medicine, Riverside Community Hospital / Hospital Corporation of America, Riverside, USA.

出版信息

Cureus. 2018 Nov 30;10(11):e3665. doi: 10.7759/cureus.3665.

DOI:10.7759/cureus.3665
PMID:30740284
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6355300/
Abstract

Distributive (vasodilatory) shock is common in patients admitted to the intensive care unit (ICU). Treating distributive shock presents a challenge, especially if a patient is tachyphylactic to commonly used vasopressors. This case report illustrates the use of a newly approved vasopressor in a patient with vasodilatory shock resulting from a motor vehicle injury. A 56-year-old man was brought to our emergency department (ED) hemodynamically unstable requiring aggressive resuscitation. The results of his evaluation were consistent with multisystem trauma for which he required intubation on arrival, and he received multiple units of blood and blood product via transfusion. The patient's condition declined despite receiving multiple vasopressors in the ICU. A few days after admission, the patient developed ischemic bowel requiring surgical resection. While his chance of survival was believed to be dismal, the use of angiotensin II (ATII) as a last resort proved to be helpful.

摘要

分布性(血管扩张性)休克在入住重症监护病房(ICU)的患者中很常见。治疗分布性休克是一项挑战,尤其是当患者对常用血管升压药产生快速耐受性时。本病例报告说明了一种新批准的血管升压药在一名因机动车损伤导致血管扩张性休克患者中的应用。一名56岁男性被送往我们的急诊科(ED),血流动力学不稳定,需要积极复苏。他的评估结果与多系统创伤一致,入院时需要插管,并且通过输血接受了多个单位的血液和血液制品。尽管在ICU中接受了多种血管升压药治疗,患者的病情仍在恶化。入院几天后,患者出现缺血性肠病,需要手术切除。虽然他的生存机会被认为渺茫,但作为最后手段使用血管紧张素II(ATII)被证明是有帮助的。

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本文引用的文献

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Vasodilatory shock in the ICU and the role of angiotensin II.重症监护病房中的血管扩张性休克与血管紧张素 II 的作用。
Curr Opin Crit Care. 2018 Aug;24(4):277-285. doi: 10.1097/MCC.0000000000000517.
2
When All Else Fails: Novel Use of Angiotensin II for Vasodilatory Shock: A Case Report.当其他方法均告失败时:血管紧张素II在血管舒张性休克中的新应用:一例报告
A A Pract. 2018 Oct 1;11(7):175-180. doi: 10.1213/XAA.0000000000000775.
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A Blast From the Past: Revival of Angiotensin II for Vasodilatory Shock.昔日重现:血管扩张性休克中血管紧张素 II 的复兴。
Ann Pharmacother. 2018 Sep;52(9):920-927. doi: 10.1177/1060028018767899. Epub 2018 Mar 27.
4
Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II.血管扩张性休克合并肾脏替代治疗患者静脉内应用血管紧张素 II 的结局。
Crit Care Med. 2018 Jun;46(6):949-957. doi: 10.1097/CCM.0000000000003092.
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Management of Refractory Vasodilatory Shock.难治性血管扩张性休克的处理。
Chest. 2018 Aug;154(2):416-426. doi: 10.1016/j.chest.2017.12.021. Epub 2018 Jan 9.
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Crit Care. 2017 Dec 28;21(1):324. doi: 10.1186/s13054-017-1896-6.
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Angiotensin II for the Treatment of Vasodilatory Shock.血管扩张性休克的血管紧张素 II 治疗。
N Engl J Med. 2017 Aug 3;377(5):419-430. doi: 10.1056/NEJMoa1704154. Epub 2017 May 21.
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Angiotensin II in Refractory Septic Shock.难治性感染性休克中的血管紧张素II
Shock. 2017 May;47(5):560-566. doi: 10.1097/SHK.0000000000000807.
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J Crit Care. 2014 Aug;29(4):500-11. doi: 10.1016/j.jcrc.2014.03.028. Epub 2014 Apr 5.
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Circulatory shock.循环性休克
N Engl J Med. 2013 Oct 31;369(18):1726-34. doi: 10.1056/NEJMra1208943.