Human factor H (beta 1H-globulin): linkage analysis.
作者信息
Kömpf J, Luckenbach C, Kloor D, Schunter F, Wernet P, Ritter H
机构信息
Institut für Anthropologie und Humangenetik der Universität, Tübingen, Federal Republic of Germany.
出版信息
Hum Genet. 1988 Jun;79(2):181-2. doi: 10.1007/BF00280562.
PMID:2968949
Abstract
Linkage data on human factor H (HF) and 22 other human genetic markers are presented. Close linkage at theta less than 0.10 can be ruled out for a series of marker systems (Rh, PGM1, ACP1, Jk, Tf, Gc, MNSs, ME2, HLA, GLO1, ORM, Gt, PI, Hp, GPT). Strong evidence for linkage was obtained for peptidase A (PEPA) with lods greater than 3.0 at theta = 0.10 in males and at theta = 0.20 for the sexes combined. From this result the HF locus can be provisionally assigned to chromosome 18.
摘要
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