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酒精销售点可达性与不良出生结局之间的关联:一项回顾性队列研究。

The association between alcohol outlet accessibility and adverse birth outcomes: A retrospective cohort study.

作者信息

Seabrook J A, Woods N, Clark A, de Vrijer B, Penava D, Gilliland J

机构信息

School of Food and Nutritional Sciences, Brescia University College, London, ON, Canada.

Department of Paediatrics, Western University, London, ON, Canada.

出版信息

J Neonatal Perinatal Med. 2018;11(1):71-77. doi: 10.3233/NPM-181741.

Abstract

BACKGROUND

Alcohol outlet accessibility is positively associated with alcohol consumption, although this relationship has not been thoroughly examined in pregnant women. The present study examines the relationship between proximity and density of alcohol outlets and risk for low birth weight (LBW: <2,500 grams) and preterm birth (PTB: <37 weeks gestational age), and is the first Canadian study to investigate this association.

METHODS

Maternal accessibility to alcohol outlets was specified using a gravity-type measure of accessibility, which provides the amount of accessibility that a given household has to liquor stores within 30-minutes of their home. All singleton newborns without congenital anomalies that were born between February 2009 and February 2014 at London Health Sciences Centre in London, Ontario, were included in this cohort.

RESULTS

The sample consisted of 25,734 live births, of which 5.8% were LBW and 7.6% were PTB. Only 2.0% of women reported alcohol use during pregnancy. Alcohol outlet gravity was positively correlated with the percentage of mothers living in poverty (rs = 0.33, p < 0.001) and in single-parent families (rs = 0.39, p < 0.001), and who self-identify as visible minorities (rs = 0.45, p < 0.001). Alcohol outlet gravity increased the odds that mothers drank alcohol during pregnancy (OR 1.05; 95% CI: 1.02, 1.07), although the association was weak. Furthermore, alcohol outlet gravity did not increase the likelihood of a LBW or PTB infant.

CONCLUSIONS

Women with high accessibility to alcohol outlets are more likely to consume alcohol during pregnancy, but greater alcohol outlet accessibility does not translate into poor birth outcomes.

摘要

背景

酒精销售点的可达性与酒精消费呈正相关,尽管这种关系在孕妇中尚未得到充分研究。本研究考察了酒精销售点的接近程度和密度与低出生体重(LBW:<2500克)和早产(PTB:妊娠<37周)风险之间的关系,这是加拿大第一项调查此关联的研究。

方法

使用重力式可达性测量方法来确定母亲对酒精销售点的可达性,该方法提供了给定家庭到其家30分钟路程内酒类商店的可达量。2009年2月至2014年2月在安大略省伦敦市伦敦健康科学中心出生的所有无先天性异常的单胎新生儿都纳入了该队列。

结果

样本包括25734例活产,其中5.8%为低出生体重儿,7.6%为早产儿。只有2.0%的女性报告在孕期饮酒。酒精销售点重力与生活在贫困中的母亲比例(rs = 0.33,p < 0.001)、单亲家庭中的母亲比例(rs = 0.39,p < 0.001)以及自我认定为少数族裔的母亲比例(rs = 0.45,p < 0.001)呈正相关。酒精销售点重力增加了母亲孕期饮酒的几率(OR 1.05;95% CI:1.02,1.07),尽管这种关联较弱。此外,酒精销售点重力并未增加低出生体重或早产婴儿的可能性。

结论

酒精销售点可达性高的女性在孕期更有可能饮酒,但更高的酒精销售点可达性并不会导致不良出生结局。

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