Liu J, Zhang J, Cheng Q J, Xu J F, Jie Z J, Jiao Y, Huang Y, Qu J M
Department of Respiratory and Critical Care Medicine, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai 200433, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2018 Apr 12;41(4):288-295. doi: 10.3760/cma.j.issn.1001-0939.2018.04.008.
To understand the current status of diagnosis and treatment of community-acquired pneumonia (CAP) among doctors in various hospitals across Shanghai, for the purpose of promoting the 2016 clinical practice guidelines for adult CAP of China. A questionnaire was designed to address the common questions in CAP management. The responses were collected via WeChat and the data were analyzed. A total of 1 254 valid questionnaires were received, 46.1% from tertiary , 26.4% from secondary and 27.5% from primary care hospitals. Of these valid respondents, 31.4% were respiratory physicians and 68.6% from non-respiratory physicians. When diagnosing CAP, 78.1% of the doctors would use chest CT in more than 50% of the patients. Regarding the tools for evaluating the severity of CAP, 60.3% of the respondents would prefer CURB-65. "Respiratory failure requiring mechanical ventilation and septic shock" were the most common criteria for admission to ICU. Blood culture was not widely used in severe CAP regardless of the level of hospitals (>0.05). The results of this survey showed that the top 5 pathogenic microorganisms of CAP were Streptococcus pneumoniae, Mycoplasma pneumoniae, Klebsiella pneumoniae, Haemophilus influenza and Chlamydia pneumoniae. For non-severe CAP patients, all the doctors tended to select monotherapy. The most frequently used antimicrobial regimen for severe CAP was third- or fourth-generation cephalosporin monotherapy. As for combination therapy, the most frequently used regimen in tertiary hospitals was "carbapenem plus vancomycin" , while in primary and secondary hospitals it was "β-lactams plus macrolides" . More doctors from primary hospitals and non-respiratory medicine would consider "complete resolution of pulmonary opacity" as the indication to discontinue antimicrobial therapy or to discharge patients, and "prolonged high fever" , "large area consolidation" , "multiple lobe-segment involvement " as the indication for corticosteroid therapy. A significantly lower proportion of doctors in secondary and tertiary hospitals would recommend patients to receive vaccination than in primary hospitals (<0.05). This questionnaire study showed that there was a gap between the ideal and the real world practice in CAP management. Efforts should be made to popularize the 2016 CAP guideline in hospitals of any level of care, especially primary hospitals, for the purpose of further standardizing CAP management in China.
为了解上海市各级医院医生对社区获得性肺炎(CAP)的诊治现状,以推广《中国成人社区获得性肺炎诊断和治疗指南(2016年版)》。设计了一份问卷以解决CAP管理中的常见问题。通过微信收集回复并进行数据分析。共收到1254份有效问卷,其中46.1%来自三级医院,26.4%来自二级医院,27.5%来自基层医院。在这些有效受访者中,31.4%为呼吸内科医生,68.6%为非呼吸内科医生。诊断CAP时,78.1%的医生会在超过50%的患者中使用胸部CT。关于评估CAP严重程度的工具,60.3%的受访者更倾向于使用CURB-65。“需要机械通气的呼吸衰竭和感染性休克”是入住ICU最常见的标准。无论医院级别如何,血培养在重症CAP中使用并不广泛(>0.05)。本次调查结果显示,CAP的前5位致病微生物为肺炎链球菌、肺炎支原体、肺炎克雷伯菌、流感嗜血杆菌和肺炎衣原体。对于非重症CAP患者,所有医生都倾向于选择单药治疗。重症CAP最常用的抗菌治疗方案是第三代或第四代头孢菌素单药治疗。至于联合治疗,三级医院最常用的方案是“碳青霉烯类加万古霉素”,而在基层和二级医院是“β-内酰胺类加大环内酯类”。基层医院和非呼吸内科的更多医生会将“肺部阴影完全消散”视为停用抗菌药物或出院的指标,将“持续高热”“大面积实变”“多叶段受累”视为使用糖皮质激素治疗的指标。二级和三级医院建议患者接种疫苗的医生比例显著低于基层医院(<0.05)。这项问卷调查研究表明,CAP管理的理想与实际临床实践之间存在差距。应努力在各级医疗机构,特别是基层医院推广《2016年CAP指南》,以进一步规范我国CAP的管理。