Zhang P Y, Xiao C
Department of Stomatology, Kunshan Hospital of Traditional Chinese Medicine, Kunshan Affiliated Hospital of Nanjing University of Chinese Medicine, Kunshan Jiangsu 215300, China.
Department of Stomatology, The First Affiliated Hospital of Soochow University, Suzhou Jiangsu 215006, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2018 Apr 9;53(4):280-283. doi: 10.3760/cma.j.issn.1002-0098.2018.04.013.
Florid cemento-osseous dysplasia (FLCOD) is a rare, extensive bone metabolism disorder, which occurs only in the jaw bone. It is usually asymptomatic for a long time and discovered incidentally during a radiological examination. The characteristics of FLCOD in the initial stages are similar to those of periapical granuloma or jaw cyst, which may lead to misdiagnosis. After the lesion is mature, the imaging findings show that radiopaque with a thin radiolucent peripheral halo, which is crucial for the diagnosis of FLCOD, but other jaw lesions have similar imaging findings. Due to the poor blood supply of the lesion, the alveolar bone of root apices of vital teeth is slow to heal after trauma, increasing the chance of infection, which can lead to the osteomyelitis of the jaws and emerge sequestrum. This paper reviews the aspects of pathogenesis, clinical characteristics, diagnosis, differential diagnosis and treatment.
florid骨化性纤维瘤(FLCOD)是一种罕见的、广泛的骨代谢紊乱疾病,仅发生于颌骨。它通常长期无症状,在影像学检查时偶然发现。FLCOD早期的特征与根尖肉芽肿或颌骨囊肿相似,可能导致误诊。病变成熟后,影像学表现为不透光区周围有一薄层透光晕,这对FLCOD的诊断至关重要,但其他颌骨病变也有类似的影像学表现。由于病变血供差,活髓牙根尖的牙槽骨外伤后愈合缓慢,增加了感染机会,可导致颌骨骨髓炎并出现死骨。本文就其发病机制、临床特点、诊断、鉴别诊断及治疗等方面进行综述。