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ClariVein™ - 新加坡多民族亚洲人群中静脉曲张机械化学消融术的一年结果

ClariVein™ - One year results of mechano-chemical ablation for varicose veins in a multi-ethnic Asian population from Singapore.

作者信息

Khor Shao N, Lei Jiang, Kam Jia W, Kum Steven, Tan Yih K, Tang Tjun Y

机构信息

1 Vascular Service, Department of General Surgery, Changi General Hospital, Singapore, Singapore.

2 Clinical Trials & Research Unit, Changi General Hospital, Singapore, Singapore.

出版信息

Phlebology. 2018 Dec;33(10):687-694. doi: 10.1177/0268355518771225. Epub 2018 Apr 24.

Abstract

OBJECTIVES

This study assessed the effectiveness and patient experience of ClariVein for varicose veins and chronic venous insufficiency (CVI) in a multi-ethnic Asian population from Singapore.

METHODS

A total of 121 patients underwent mechano-chemical ablation. Patients were reviewed at an interval of one week, and at 3, 6 and 12 months post procedure and underwent Duplex ultrasound with patient satisfaction assessment.

RESULTS

At three months of follow-up, the great saphenous vein and short saphenous vein occlusion rates were 90.8% and 96.0%, respectively. At six months of follow-up, the GSV and short saphenous vein occlusion rates were 86.9% and 90.9%, respectively. At one year, great saphenous vein and short saphenous vein occlusion rates were 84.8% and 94.3%, respectively.

CONCLUSIONS

Early results are similar to what is described so far in the mechano-chemical ablation literature but recurrences are more than expected at one year. This is disappointing but is tempered by the fact that the majority of patients were asymptomatic and required no reintervention.

摘要

目的

本研究评估了ClariVein在新加坡多民族亚洲人群中治疗静脉曲张和慢性静脉功能不全(CVI)的有效性及患者体验。

方法

共有121例患者接受了机械化学消融治疗。术后每隔一周、3个月、6个月和12个月对患者进行复查,并进行双功超声检查及患者满意度评估。

结果

随访3个月时,大隐静脉和小隐静脉闭塞率分别为90.8%和96.0%。随访6个月时,大隐静脉和小隐静脉闭塞率分别为86.9%和90.9%。1年时,大隐静脉和小隐静脉闭塞率分别为84.8%和94.3%。

结论

早期结果与机械化学消融文献中迄今所描述的相似,但1年时复发率高于预期。这令人失望,但多数患者无症状且无需再次干预这一事实缓和了这种情况。

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