Sritharan Sajitha Sophia, Frandsen Jens Lundby, Omland Øyvind, Bruun Jens Meldgaard
Ugeskr Laeger. 2018 Apr 9;180(15).
Malignant pleural mesothelioma (MPM) is a rare cancer with a poor prognosis. The disease is of importance, since the incidence in Denmark is increasing despite cessation of the use of asbestos in the 1980s. MPM has a long latency period, and the first symptom is often dyspnoea, typically caused by pleural effusion. The diagnosis is a challenge, because cytology often is non-conclusive, and thoracoscopy is needed to obtain biopsies for immunohistochemistry. The occupational history is important, since the patients are entitled to compensation. The treatment is often limited to palliation.
恶性胸膜间皮瘤（MPM）是一种预后较差的罕见癌症。这种疾病很重要，因为尽管丹麦在20世纪80年代就停止使用石棉，但发病率仍在上升。MPM有很长的潜伏期，首发症状通常是呼吸困难，典型原因是胸腔积液。诊断颇具挑战性，因为细胞学检查往往无法确诊，需要进行胸腔镜检查以获取活检组织用于免疫组织化学分析。职业病史很重要，因为患者有权获得赔偿。治疗通常仅限于姑息治疗。
