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在中国东南部,妇女恶性腹膜间皮瘤和胸膜间皮瘤与石棉纺织生产有关:28 例分析。

Asbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China.

机构信息

Department of Pathology, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province, 315400, China.

Department of Pathology, Tokyo Women's Medical University, Yachiyo Medical Center, Owada-Shinden 477-96, Yachiyo, Chiba, 276-8524, Japan.

出版信息

Am J Ind Med. 2015 Oct;58(10):1040-9. doi: 10.1002/ajim.22494. Epub 2015 Jul 6.

DOI:10.1002/ajim.22494
PMID:
26147229
Abstract

BACKGROUND

Chrysotile had been used in asbestos textile workshops in Southeast China but a clear relation to mesothelioma is lacking.

METHODS

All patients diagnosed with mesothelioma from 2003 to 2010 at Yuyao People's Hospital were re-evaluated by multiple expert pathologists with immunohistochemistry and asbestos exposure data were collected.

RESULTS

Of 43 patients with a mesothelioma diagnosis, 19 peritoneal and nine pleural cases were finally diagnosed as mesothelioma. All were females, and the mean age of the patients with peritoneal or pleural mesothelioma was 52.4 and 58.2 years, respectively. All these cases had a history of domestic or occupational exposure to chrysotile. Two-thirds of the patients were from two adjoining towns with multiple small asbestos textile workshops. Contamination of tremolite was estimated to be less than 0.3%.

CONCLUSIONS

This is a report of mesothelioma in women exposed to chrysotile asbestos at home and at work, with an over-representation of peritoneal mesothelioma.

摘要

背景

中国东南部的石棉纺织车间曾使用过温石棉,但与间皮瘤之间缺乏明确的关系。

方法

对 2003 年至 2010 年在余姚市人民医院诊断为间皮瘤的所有患者进行重新评估,由多位专家病理学家进行免疫组化检查,并收集石棉暴露数据。

结果

在 43 名间皮瘤诊断患者中,最终诊断为间皮瘤的腹膜 19 例,胸腔 9 例。所有患者均为女性,腹膜间皮瘤或胸腔间皮瘤患者的平均年龄分别为 52.4 岁和 58.2 岁。所有这些病例均有家庭或职业接触温石棉的病史。三分之二的患者来自两个相邻的城镇,这些城镇有多个小型石棉纺织车间。估计透闪石污染低于 0.3%。

结论

这是一份报告,报告了女性在家中和工作中接触温石棉石棉引起的间皮瘤,腹膜间皮瘤的发病率偏高。

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