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[耐万古霉素肠球菌感染的治疗]

[Treatment of vancomycin-resistant enterococcal infections].

作者信息

Lund Lars Christian, Holzknecht Barbara Juliane, Justesen Ulrik Stenz

出版信息

Ugeskr Laeger. 2018 Apr 16;180(16).

PMID:29690991
Abstract

Vancomycin-resistant enterococci (VRE) are a growing healthcare concern, and since 2012 the incidence has increased eightfold in Denmark. Treatment options for infections with ampicillin-resistant VRE are sparse, and there are no Danish guidelines concerning this topic. For treatment of uncomplicated VRE urinary tract infections, ciprofloxacin or nitrofurantoin can be used. The mainstay of treatment of bacteraemia and other severe infections caused by VRE is linezolid or high-dose daptomycin. Combination treatment is recommended for complicated infections and/or prolonged therapy.

摘要

耐万古霉素肠球菌(VRE)日益引起医疗保健领域的关注,自2012年以来,丹麦的发病率增长了八倍。耐氨苄西林VRE感染的治疗选择有限,丹麦也没有关于这一主题的指南。对于单纯性VRE尿路感染的治疗,可使用环丙沙星或呋喃妥因。治疗由VRE引起的菌血症和其他严重感染的主要药物是利奈唑胺或高剂量达托霉素。对于复杂性感染和/或延长治疗,建议采用联合治疗。

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[Treatment of vancomycin-resistant enterococcal infections].[耐万古霉素肠球菌感染的治疗]
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引用本文的文献

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A Review of Detection Methods for Vancomycin-Resistant (VRE) Genes: From Conventional Approaches to Potentially Electrochemical DNA Biosensors.万古霉素耐药 (VRE) 基因检测方法的研究进展:从传统方法到潜在电化学 DNA 生物传感器。
Biosensors (Basel). 2023 Feb 18;13(2):294. doi: 10.3390/bios13020294.
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The Global Prevalence of Daptomycin, Tigecycline, and Linezolid-Resistant and Strains From Human Clinical Samples: A Systematic Review and Meta-Analysis.来自人类临床样本的达托霉素、替加环素和耐利奈唑胺菌株的全球流行率:一项系统评价和荟萃分析。
Front Med (Lausanne). 2021 Sep 10;8:720647. doi: 10.3389/fmed.2021.720647. eCollection 2021.