Grobholz R
Institut für Pathologie, Kantonsspital Aarau, Tellstrasse 25, 5001, Aarau, Schweiz.
Medizinische Fakultät, Universität Zürich, Zürich, Schweiz.
Pathologe. 2018 May;39(3):228-235. doi: 10.1007/s00292-018-0431-0.
Digital pathology (DP) and whole-slide imaging (WSI) technology have matured substantially over the last few years. Meanwhile, commercial systems are available that can be used in routine practice.
Illustration of DP experiences in a routine diagnostic setting.
A DP system offers several advantages: 1) glass slides are no longer unique; 2) access to cases is possible from any location; 3) digital image analysis can be applied; and 4) archived WSI can be easily accessed. From this point, several secondary advantages arise: a) the slide compilation of the case and the case assignment is fast and safe; b) carrying cases to the pathologist is obsolete and paperless work is possible; c) WSI can be used for a second opinion and be accessible in remote locations; d) WSI of referred cases are still accessible after returning the slides; e) histological images can easily be provided in tumor boards; f) the office desk is clean; and g) a "home office" is possible. To introduce a DP system, a comprehensive workflow analysis is needed that clarifies the needs and wishes of the respective institute. In order to optimally meet the requirements, open DP platforms are of particular advantage, because they enable the integration of scanners from various manufacturers. Further developments in image analysis, such as virtual tissue reconstruction, could enrich the diagnostic process in the future and improve treatment quality.
在过去几年中，数字病理学（DP）和全切片成像（WSI）技术已取得显著成熟。与此同时，有可供常规实践使用的商业系统。
阐述在常规诊断环境中的数字病理学经验。
数字病理学系统具有若干优势：1）载玻片不再独一无二；2）可从任何地点访问病例；3）可应用数字图像分析；4）可轻松访问存档的全切片图像。由此产生了若干次要优势：a）病例的玻片汇编和病例分配快速且安全；b）将病例送到病理学家处已过时，无纸办公成为可能；c）全切片图像可用于获取二次诊断意见，且在偏远地区也可访问；d）退回玻片后，转诊病例的全切片图像仍可访问；e）组织学图像可轻松在肿瘤讨论会上提供；f）办公桌整洁；g）“在家办公”成为可能。要引入数字病理学系统，需要进行全面的工作流程分析，以明确各机构的需求和愿望。为了最佳地满足要求，开放式数字病理学平台具有特别优势，因为它们能够集成来自不同制造商的扫描仪。图像分析的进一步发展，如虚拟组织重建，未来可能会丰富诊断过程并提高治疗质量。
