Saha Aniruddha, Mandal Palash Kumar, Manna Anupam, Khan Kalyan, Pal Subrata
Anandaloke Sonoscan Centre, North Bengal Medical College, Siliguri, India.
Department of Pathology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India.
J Lab Physicians. 2018 Apr-Jun;10(2):248-250. doi: 10.4103/JLP.JLP_167_16.
Well-differentiated papillary mesothelioma is a rare tumor occurring predominantly in the peritoneum of young women, a few with history of asbestos exposure. A 28-year-old woman presented with ascites and pain abdomen. Ultrasonography and computed tomography scan of the abdomen revealed a mass in the retroperitoneum measuring 15 cm × 12 cm. Histopathological examination along with immunohistochemistry (IHC) confirmed it to be a papillary mesothelioma in the peritoneum. It is difficult to differentiate from more common malignant mesothelioma and papillary adenocarcinoma, which also have poorer prognosis. The difficulty can be resolved by clinico-radiological correlation along with histopathological examination and IHC.
高分化乳头状间皮瘤是一种罕见肿瘤,主要发生于年轻女性的腹膜,少数有石棉接触史。一名28岁女性因腹水和腹痛就诊。腹部超声和计算机断层扫描显示腹膜后有一大小为15 cm×12 cm的肿块。组织病理学检查及免疫组织化学(IHC)证实为腹膜乳头状间皮瘤。它很难与更常见的恶性间皮瘤和乳头状腺癌相鉴别,而后两者预后也较差。通过临床影像学关联、组织病理学检查及免疫组织化学可解决这一鉴别难题。