药物难治性癫痫患者的胼胝体前部切开术：颅内脑电图结果与癫痫发作结局
Anterior corpus callosotomy in patients with drug-resistant epilepsy: Invasive EEG findings and seizure outcomes.
作者信息
Taraschenko Olga, Pedavally Swetha, Samson Kaeli K, Puccioni Mark J, Madhavan Deepak
机构信息
Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, United States.
Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE, United States.
出版信息
Epilepsy Behav Case Rep. 2017 Dec 8;9:12-18. doi: 10.1016/j.ebcr.2017.12.001. eCollection 2018.
Corpus callosotomy (CC) is used in patients with drug-resistant seizures who are not candidates for excisional surgery and failed neurostimulation. We examined ictal scalp and intracranial electroencephalogram (iEEG) recordings in 16 patients being evaluated for anterior CC alone or CC in combination with focal resection, to determine the role of the iEEG in predicting postoperative seizure outcomes. In our cohort, CC improved generalized atonic seizures and focal seizures with impaired awareness but did not alter outcomes for generalized tonic-clonic or tonic seizures. Invasive EEG prior to CC did not refine the prediction of postsurgical seizure outcomes in patients with inconclusive scalp EEG.
胼胝体切开术（CC）用于药物难治性癫痫患者，这些患者不适合进行切除性手术且神经刺激治疗失败。我们检查了16例仅接受前胼胝体切开术或胼胝体切开术联合局灶性切除评估患者的发作期头皮和颅内脑电图（iEEG）记录，以确定iEEG在预测术后癫痫发作结果中的作用。在我们的队列中，CC改善了全身性失张力性发作和伴有意识障碍的局灶性发作，但未改变全身性强直阵挛性发作或强直性发作的结果。对于头皮脑电图不确定的患者，CC术前的侵入性脑电图并未改善对术后癫痫发作结果的预测。
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