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Explosive bullous pemphigoid with high serum total IgE: Serum IgE as a biomarker that reflects disease activity.

作者信息

Kwon Hyun Jung, Ahn Ga Ram, Choi Sun Young, Li Kapsok, Seo Seong Jun

机构信息

Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

出版信息

JAAD Case Rep. 2018 Apr 4;4(4):352-354. doi: 10.1016/j.jdcr.2017.09.011. eCollection 2018 May.

DOI:10.1016/j.jdcr.2017.09.011
PMID:29693068
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5911796/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8899/5911796/11e4b586cfa8/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8899/5911796/62baab15b78c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8899/5911796/3a66bb2b001d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8899/5911796/2b8c3032e917/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8899/5911796/11e4b586cfa8/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8899/5911796/62baab15b78c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8899/5911796/3a66bb2b001d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8899/5911796/2b8c3032e917/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8899/5911796/11e4b586cfa8/gr4.jpg

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Complete Remission in a Patient with Treatment Refractory Bullous Pemphigoid after a Single Dose of Omalizumab.单剂量奥马珠单抗治疗后难治性大疱性类天疱疮患者实现完全缓解
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本文引用的文献

1
Detection of IgE autoantibodies to BP180 and BP230 and their relationship to clinical features in bullous pemphigoid.检测大疱性类天疱疮患者 IgE 自身抗体对 BP180 和 BP230 的反应与其临床特征的关系。
Br J Dermatol. 2017 Jul;177(1):141-151. doi: 10.1111/bjd.15114. Epub 2017 Apr 12.
2
Successful treatment of bullous pemphigoid with omalizumab as corticosteroid-sparing agent: report of two cases and review of literature.以奥马珠单抗作为糖皮质激素节约剂成功治疗大疱性类天疱疮：两例报告及文献复习
J Eur Acad Dermatol Venereol. 2016 Oct;30(10):1778-1782. doi: 10.1111/jdv.13758. Epub 2016 Jun 29.
3
IgE-mediated mechanisms in bullous pemphigoid and other autoimmune bullous diseases.
大疱性类天疱疮及其他自身免疫性大疱病中的IgE介导机制。
Expert Rev Clin Immunol. 2016;12(3):267-77. doi: 10.1586/1744666X.2016.1123092. Epub 2015 Dec 16.
4
Eosinophil localization to the basement membrane zone is autoantibody- and complement-dependent in a human cryosection model of bullous pemphigoid.在大疱性类天疱疮的人体冰冻切片模型中，嗜酸性粒细胞定位于基底膜带是自身抗体和补体依赖性的。
Exp Dermatol. 2016 Jan;25(1):50-5. doi: 10.1111/exd.12883. Epub 2015 Nov 23.
5
Human eosinophils express the high affinity IgE receptor, FcεRI, in bullous pemphigoid.在大疱性类天疱疮中，人类嗜酸性粒细胞表达高亲和力IgE受体FcεRI。
PLoS One. 2014 Sep 25;9(9):e107725. doi: 10.1371/journal.pone.0107725. eCollection 2014.
6
Omalizumab therapy for bullous pemphigoid.奥马珠单抗治疗大疱性类天疱疮。
J Am Acad Dermatol. 2014 Sep;71(3):468-74. doi: 10.1016/j.jaad.2014.04.053. Epub 2014 Jun 20.
7
Mortality of patients with bullous pemphigoid in Korea.韩国大疱性类天疱疮患者的死亡率。
J Am Acad Dermatol. 2014 Oct;71(4):676-83. doi: 10.1016/j.jaad.2014.05.006. Epub 2014 Jun 12.
8
Severity score indexes for blistering diseases.水疱性疾病严重程度评分指数。
Clin Dermatol. 2012 Jan-Feb;30(1):108-13. doi: 10.1016/j.clindermatol.2011.03.017.
9
Correlation of IgE autoantibody to BP180 with a severe form of bullous pemphigoid.IgE自身抗体与BP180的相关性与严重型大疱性类天疱疮。
Arch Dermatol. 2008 Jan;144(1):41-8. doi: 10.1001/archdermatol.2007.9.
10
Serum IgE levels in patients with bullous pemphigoid.大疱性类天疱疮患者的血清免疫球蛋白E水平。
Acta Derm Venereol. 1985;65(3):273-4.