Chirossel P, Barbe R, Clermont A, Revel D, Amiel M
Laboratoire d'exploration fonctionnelle vasculaire, UA, CNRS, 1216, Hôpital Cardiologique, Lyon.
J Mal Vasc. 1988;13(2):89-94.
Numerous studies in the literature have proven the fact that a critical size appears during the stenosis evolution. The work presented is a non invasive approach of this value, with correlation to the invasive results. The study was realized on a homogeneous group of 23 arteriopathic patients, selected for iliac artery angioplasty procedure.
Patients selection: twenty-three patients including 24 angioplasty procedures have been selected on a 21 month time study. Invasive data: two measurements are realized during angioplasty: trans-stenotic pressure gradient before and after angioplasty. stenosis calibration: both diameter and section have been calculated on radiological films. Non invasive data: a standard Doppler test is performed on lower limbs. Two parameters are compared with the invasive data: the ascending time of velocity curve at the common femoral level. the systolic pressure index (peripheral pressure/radial pressure).
Some discordant results open the discussion about angioplasty as a "gold standard", specially with a geometrical analysis. Bad precision in non regular stenosis. Hemodynamic consequences of turbulent stenosis are not evaluated. Clinical interest of critical stenotic notion is underlined.(ABSTRACT TRUNCATED AT 250 WORDS)
文献中的大量研究已证实,在狭窄病变发展过程中会出现一个临界值。本文介绍的是一种获取该临界值的非侵入性方法,并将其与侵入性检测结果进行相关性分析。该研究针对一组23名因髂动脉血管成形术而入选的动脉病变患者展开。
患者选择:在为期21个月的研究中,选取了23名患者,共进行了24次血管成形术。侵入性数据:血管成形术中进行两项测量:血管成形术前、后的跨狭窄压力梯度。狭窄校准:在放射影像上计算直径和截面积。非侵入性数据:对下肢进行标准多普勒检查。将两个参数与侵入性数据进行比较:股总动脉水平处速度曲线的上升时间;收缩压指数(外周压力/桡动脉压力)。
1)临界狭窄——侵入性技术(图1):跨狭窄压力梯度与狭窄测量值呈双曲线相关性。发现临界狭窄水平在直径上为60%,在截面积上为80%。2)临界狭窄——非侵入性技术:将狭窄测量值与上升时间(图2)以及静息时的压力指数(图3)进行比较,显示出相同类型的曲线。发现临界狭窄水平与侵入性技术相同。
一些不一致的结果引发了关于血管成形术作为“金标准”的讨论,特别是在进行几何分析时。不规则狭窄的精度较差。未评估湍流性狭窄的血流动力学后果。强调了临界狭窄概念的临床意义。(摘要截断于250字)