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[临界动脉狭窄的概念:髂动脉腔内血管成形术前和术后通过血管造影方法及多普勒技术获得的测量模型的价值]

[The concept of critical arterial stenosis: value of a model of measures obtained by an angiographic method and the Doppler technic before and after transluminal angioplasty of the iliac arteries].

作者信息

Chirossel P, Barbe R, Clermont A, Revel D, Amiel M

机构信息

Laboratoire d'exploration fonctionnelle vasculaire, UA, CNRS, 1216, Hôpital Cardiologique, Lyon.

出版信息

J Mal Vasc. 1988;13(2):89-94.

PMID:2969404
Abstract

INTRODUCTION

Numerous studies in the literature have proven the fact that a critical size appears during the stenosis evolution. The work presented is a non invasive approach of this value, with correlation to the invasive results. The study was realized on a homogeneous group of 23 arteriopathic patients, selected for iliac artery angioplasty procedure.

MATERIAL AND METHODS

Patients selection: twenty-three patients including 24 angioplasty procedures have been selected on a 21 month time study. Invasive data: two measurements are realized during angioplasty: trans-stenotic pressure gradient before and after angioplasty. stenosis calibration: both diameter and section have been calculated on radiological films. Non invasive data: a standard Doppler test is performed on lower limbs. Two parameters are compared with the invasive data: the ascending time of velocity curve at the common femoral level. the systolic pressure index (peripheral pressure/radial pressure).

RESULTS

  1. Critical stenosis--invasive techniques (fig. 1): trans-stenotic pressure gradient versus stenotic measurements shaw an hyperbolic correlation. The critical stenotic level is found to be 60% in diameter and 80% in section. 2) Critical stenosis--non invasive techniques: stenotic measurements compared to ascending time (fig. 2) as well as pressure index at rest (fig. 3) shaw the same type of curve. The critical stenotic level is found to be the same than with invasive techniques.

DISCUSSION

Some discordant results open the discussion about angioplasty as a "gold standard", specially with a geometrical analysis. Bad precision in non regular stenosis. Hemodynamic consequences of turbulent stenosis are not evaluated. Clinical interest of critical stenotic notion is underlined.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

引言

文献中的大量研究已证实,在狭窄病变发展过程中会出现一个临界值。本文介绍的是一种获取该临界值的非侵入性方法,并将其与侵入性检测结果进行相关性分析。该研究针对一组23名因髂动脉血管成形术而入选的动脉病变患者展开。

材料与方法

患者选择:在为期21个月的研究中,选取了23名患者,共进行了24次血管成形术。侵入性数据:血管成形术中进行两项测量:血管成形术前、后的跨狭窄压力梯度。狭窄校准:在放射影像上计算直径和截面积。非侵入性数据:对下肢进行标准多普勒检查。将两个参数与侵入性数据进行比较:股总动脉水平处速度曲线的上升时间;收缩压指数(外周压力/桡动脉压力)。

结果

1)临界狭窄——侵入性技术(图1):跨狭窄压力梯度与狭窄测量值呈双曲线相关性。发现临界狭窄水平在直径上为60%,在截面积上为80%。2)临界狭窄——非侵入性技术:将狭窄测量值与上升时间(图2)以及静息时的压力指数(图3)进行比较,显示出相同类型的曲线。发现临界狭窄水平与侵入性技术相同。

讨论

一些不一致的结果引发了关于血管成形术作为“金标准”的讨论,特别是在进行几何分析时。不规则狭窄的精度较差。未评估湍流性狭窄的血流动力学后果。强调了临界狭窄概念的临床意义。(摘要截断于250字)

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