Silva Grazielle Dias da, Andrade Eli Iola Gurgel, Cherchiglia Mariângela Leal, Almeida Alessandra Maciel, Guerra Júnior Augusto Afonso, Acurcio Francisco de Assis
Fundação Hemominas, Secretaria de Estado da Saúde de Minas Gerais, Belo Horizonte, MG, Brasil,
Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.
Cien Saude Colet. 2018 Apr;23(4):1241-1253. doi: 10.1590/1413-81232018234.16352016.
Rheumatoid arthritis (RA) is a chronic condition that affects about 1% of the adult population. In a historical cohort of Minas Gerais State, 11,573 RA patients registered in the Outpatient Information System (SIA) between 2008 and 2013 were identified. For this study we adopted the public funding body's perspective and the values were adjusted by the national inflation index (IPCA) of December 2015. Etanercept was the most expensive treatment. The mean cohort age was 52 years old and most of the patients were women. Multiple regression analysis indicated a negative association between higher expenditure and age, female sex, and diagnosis at entry in the cohort and positive association between high expenditure and the Human Development Index (HDI) of the municipality and use of tumor necrosis factor agents. This study identified the factors that have an impact on RA drug treatment expenditure. Also, we showed that methods that enable extracting demographic and expenditure data of administrative information systems may represent important tools in the construction of economic studies to subsidize economic health evaluations, especially from the standpoint of the managers.
类风湿性关节炎（RA）是一种慢性病，影响约1%的成年人口。在米纳斯吉拉斯州的一个历史队列中，识别出了2008年至2013年期间在门诊信息系统（SIA）登记的11573例RA患者。在本研究中，我们采用了公共资助机构的视角，并根据2015年12月的国家通货膨胀指数（IPCA）对数值进行了调整。依那西普是最昂贵的治疗药物。队列的平均年龄为52岁，大多数患者为女性。多元回归分析表明，较高的支出与年龄、女性性别、队列入组时的诊断呈负相关，而高支出与城市的人类发展指数（HDI）和肿瘤坏死因子药物的使用呈正相关。本研究确定了影响RA药物治疗支出的因素。此外，我们表明，能够提取行政信息系统的人口统计和支出数据的方法可能是构建经济研究以辅助经济健康评估的重要工具，尤其是从管理者的角度来看。
