University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
King's College London, London, UK.
Nat Rev Dis Primers. 2018 Apr 26;4:18022. doi: 10.1038/nrdp.2018.22.
Pregnancy is a complex and vulnerable period that presents a number of challenges to women, including the development of postpartum psychiatric disorders (PPDs). These disorders can include postpartum depression and anxiety, which are relatively common, and the rare but more severe postpartum psychosis. In addition, other PPDs can include obsessive-compulsive disorder, post-traumatic stress disorder and eating disorders. The aetiology of PPDs is a complex interaction of psychological, social and biological factors, in addition to genetic and environmental factors. The goals of treating postpartum mental illness are reducing maternal symptoms and supporting maternal-child and family functioning. Women and their families should receive psychoeducation about the illness, including evidence-based discussions about the risks and benefits of each treatment option. Developing effective strategies in global settings that allow the delivery of targeted therapies to women with different clinical phenotypes and severities of PPDs is essential.
妊娠是一个复杂而脆弱的时期，女性会面临许多挑战，包括产后精神障碍（PPD）的发生。这些障碍包括产后抑郁症和焦虑症，这些相对常见，以及罕见但更严重的产后精神病。此外，其他 PPD 还包括强迫症、创伤后应激障碍和饮食障碍。PPD 的病因是心理、社会和生物因素的复杂相互作用，此外还有遗传和环境因素。治疗产后精神疾病的目标是减轻产妇的症状，支持母婴和家庭功能。应向妇女及其家属提供关于该疾病的心理教育，包括关于每种治疗选择的风险和益处的基于证据的讨论。在全球环境中制定有效的策略，为具有不同临床表型和 PPD 严重程度的妇女提供靶向治疗至关重要。
