Ballin A, Bigl H, Ferner S, Fiebig H, Leonhardt P, Neubert R, Cebulla M
Robert-Koch-Klinik, Bezirkskrankenhaus für Lungenkrankheiten Leipzig, DDR.
Z Erkr Atmungsorgane. 1988;170(2):108-17.
The activity of alveolitis in 25 patients with pulmonary sarcoidosis was determined by analysis of T-Lymphocytes and their subpopulations collected by broncho-alveolar lavage. The characterization of the lymphocytes was performed with monoclonal antibodies (BL-series). An amount of T-lymphocytes higher than 28% of all cells and a proportion of T4/T8-lymphocytes of 8:1 and over are signs of the activity of the alveolitis and an indication for corticoid therapy.
通过对25例肺结节病患者经支气管肺泡灌洗收集的T淋巴细胞及其亚群进行分析,测定肺泡炎的活性。使用单克隆抗体(BL系列)对淋巴细胞进行表征。T淋巴细胞数量高于所有细胞的28%以及T4/T8淋巴细胞比例达到8:1及以上是肺泡炎活性的标志,也是进行皮质类固醇治疗的指征。