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艺术创造力与精神分裂症、双相情感障碍和单相抑郁的风险:一项基于瑞典人群的病例对照研究和同胞对分析。

Artistic creativity and risk for schizophrenia, bipolar disorder and unipolar depression: a Swedish population-based case-control study and sib-pair analysis.

机构信息

Institute of Psychiatry,Psychology and Neuroscience,Kings College London,UK.

Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,SwedenandWarneford Hospital,Oxford,UK.

出版信息

Br J Psychiatry. 2018 Jun;212(6):370-376. doi: 10.1192/bjp.2018.23. Epub 2018 Apr 26.

DOI:10.1192/bjp.2018.23
PMID:29697041
Abstract

BACKGROUND

Many studies have addressed the question of whether mental disorder is associated with creativity, but high-quality epidemiological evidence has been lacking.AimsTo test for an association between studying a creative subject at high school or university and later mental disorder.

METHOD

In a case-control study using linked population-based registries in Sweden (N = 4 454 763), we tested for associations between tertiary education in an artistic field and hospital admission with schizophrenia (N = 20 333), bipolar disorder (N = 28 293) or unipolar depression (N = 148 365).

RESULTS

Compared with the general population, individuals with an artistic education had increased odds of developing schizophrenia (odds ratio = 1.90, 95% CI = [1.69; 2.12]) bipolar disorder (odds ratio = 1.62 [1.50; 1.75]) and unipolar depression (odds ratio = 1.39 [1.34; 1.44]. The results remained after adjustment for IQ and other potential confounders.

CONCLUSIONS

Students of artistic subjects at university are at increased risk of developing schizophrenia, bipolar disorder and unipolar depression in adulthood.Declaration of interestNone.

摘要

背景

许多研究都探讨了精神障碍是否与创造力有关,但一直缺乏高质量的流行病学证据。

目的

检验高中或大学时学习创造性学科与日后精神障碍之间的关联。

方法

我们采用瑞典基于人群的登记数据进行了一项病例对照研究(N=4 454 763),检验了接受艺术领域高等教育与精神分裂症(N=20 333)、双相情感障碍(N=28 293)或单相抑郁(N=148 365)住院之间的关联。

结果

与普通人群相比,接受艺术教育的个体出现精神分裂症(比值比=1.90,95%置信区间[1.69;2.12])、双相情感障碍(比值比=1.62 [1.50;1.75])和单相抑郁(比值比=1.39 [1.34;1.44])的几率增加。在调整智商和其他潜在混杂因素后,结果仍然成立。

结论

大学艺术学科的学生在成年后患精神分裂症、双相情感障碍和单相抑郁的风险增加。

利益声明

无。

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