Iurenev A P, D'iakonova E G, Tolstov A N, Dubov P B, Nesterova A L, Gerashchenko Iu S
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1988;11(1):19-23.
23 patients with hypertrophic cardiomyopathy (HCMP) and 19 patients with stage II of essential hypertension (EH) with left ventricular asymmetric hypertrophy (ASH) were examined. Echocardiography demonstrated significantly more manifest hypertrophy of interventricular septum and higher coefficient of asymmetry in patients with HCMP compared to those with EH while left ventricular myocardium mass was equal in both groups. Phase-volumetric analysis exhibited in all the patients deterioration of myocardial relaxation processes. EKG-monitoring showed a significant increase in frequency of supraventricular rhythm disturbances in patients with HCMP while no reliable differences in total frequency of rhythm and conduction disturbances were registered. Regular adequate antihypertensive therapy resulted in patients with EH in decrease of ASH degree caused by regression of interventricular septum hypertrophy. In natural course of EH the ASH degree also decreased, but in this case because of increased hypertrophy of left ventricular posterior wall. The patients with HCMP were followed for 1-1.5 years. Drug therapy produced no significant changes in left ventricular myocardium mass as well as character of degree of ASH.
对23例肥厚型心肌病（HCMP）患者和19例伴有左心室不对称肥厚（ASH）的II期原发性高血压（EH）患者进行了检查。超声心动图显示，与EH患者相比，HCMP患者的室间隔肥厚更明显，不对称系数更高，而两组的左心室心肌质量相等。相位容积分析显示，所有患者的心肌舒张过程均恶化。心电图监测显示，HCMP患者的室上性心律失常频率显著增加，而节律和传导障碍的总频率无可靠差异。规律、适当的抗高血压治疗使EH患者因室间隔肥厚消退导致的ASH程度降低。在EH的自然病程中，ASH程度也会降低，但在这种情况下是由于左心室后壁肥厚增加。对HCMP患者进行了1至1.5年的随访。药物治疗对左心室心肌质量以及ASH程度特征没有产生显著变化。
