Department of Mathematics and Statistics, University of Limerick, Limerick, Ireland.
Sports Spine Centre, Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar.
Pain. 2018 Aug;159(8):1631-1640. doi: 10.1097/j.pain.0000000000001251.
Pain significantly restricts the quality of life and well-being of older adults. With our increasingly ageing population, it is important to examine whether differing classes of biopsychosocial risk factors can predict the development of pain in older adults. Latent class analysis provides a model-based approach to identifying underlying subgroups in a population, based on some measured characteristics. In this study, latent class analysis was used to identify biopsychosocial risk classes in people aged 50 years and older, from The Irish Longitudinal Study on Ageing, who reported not often being troubled by pain at wave 1 and completed the 2-year follow-up at wave 2 (n = 4458). Four classes were identified based on 11 potential risk factors at wave 1. These classes were characterised as "Low Risk," "Physical Health Risk," "Mental Health Risk," and "High Risk." The Low-Risk class accounted for over half the sample (51.2%), whereas the High-Risk class represented 7.8% of the sample. At follow-up (wave 2), 797 (17.9%) participants reported being troubled by pain. Associations between the biopsychosocial risk classes and developing pain were examined using logistic regression, adjusting for sociodemographic variables. The High-Risk class was more likely to develop pain compared with the Low-Risk class (adjusted OR = 3.16, 95% CI = 2.40-4.16). These results add to existing data in other populations supporting the role of a range of biopsychosocial risk factors that increase the risk of developing pain. These findings have important implications for the identification, and potential moderation, of these risk factors.
疼痛极大地限制了老年人的生活质量和幸福感。随着人口老龄化的加剧,重要的是要研究不同类别的生物心理社会风险因素是否可以预测老年人疼痛的发展。潜在类别分析提供了一种基于模型的方法,可以根据一些测量特征来识别人群中的潜在亚组。在这项研究中,使用潜在类别分析来识别 50 岁及以上的爱尔兰老龄化纵向研究人群中的生物心理社会风险类别,这些人在第 1 波报告不经常被疼痛困扰,并在第 2 波(n = 4458)完成了 2 年随访。基于第 1 波的 11 个潜在风险因素,确定了 4 个类别。这些类别特征为“低风险”、“身体健康风险”、“心理健康风险”和“高风险”。低风险类别的样本占比超过一半(51.2%),而高风险类别的样本占比为 7.8%。在随访(第 2 波)中,有 797(17.9%)名参与者报告有疼痛困扰。使用逻辑回归检验生物心理社会风险类别的关联与疼痛的发展,调整了社会人口统计学变量。与低风险类别的参与者相比,高风险类别的参与者更有可能发展为疼痛(调整后的 OR = 3.16,95%CI = 2.40-4.16)。这些结果增加了其他人群中现有的数据,支持一系列增加疼痛发展风险的生物心理社会风险因素的作用。这些发现对这些风险因素的识别和潜在调节具有重要意义。