Health Economics, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.
Department of Economics, Lund University, Lund, Sweden.
Transplantation. 2018 Aug;102(8):1375-1381. doi: 10.1097/TP.0000000000002228.
Kidney transplantation is considered a superior treatment for end-stage renal disease compared with dialysis although little is known about the wider effects, especially on labor market outcomes. The objective is to estimate the treatment effect of kidney transplantation compared with dialysis on labor market outcomes, controlling for the nonrandom selection into treatment.
The average treatment effect is estimated using an inverse-probability weighting regression adjustment approach on all patients in renal replacement therapy 1995 to 2012.
Kidney transplantation is associated with a treatment advantage over dialysis on employment, labor force participation, early retirement, and labor income. The probability of being employed 1 year after treatment is 21 (95% confidence interval, 16-25) percentage points higher for transplantation. The positive effect increases to 38 (95% confidence interval, 30-46) percentage points after 5 years, mainly due to worsening outcomes on dialysis. The effect on labor income is mainly mediated through employment probability. The productivity gains of transplantation compared to dialysis amounts to &OV0556;33 000 over 5 years.
Transplantation is superior to dialysis in terms of potential to return to work as well as in terms of labor income and risk of early retirement, after controlling for treatment selection. This positive effect increases over time after transplantation.
与透析相比,肾移植被认为是治疗终末期肾病的一种更好的方法,尽管对于更广泛的影响(尤其是对劳动力市场结果的影响)知之甚少。目的是估计肾移植与透析相比对劳动力市场结果的治疗效果,同时控制治疗的非随机选择。
使用逆概率加权回归调整方法对 1995 年至 2012 年所有接受肾脏替代治疗的患者进行平均治疗效果估计。
与透析相比,肾移植在就业、劳动力参与率、提前退休和劳动力收入方面具有治疗优势。治疗后 1 年的就业率高 21 个百分点(95%置信区间,16-25),移植后 5 年的这一积极影响增加到 38 个百分点(95%置信区间,30-46),主要是由于透析结果恶化。对劳动力收入的影响主要通过就业概率来实现。与透析相比,移植的生产力收益在 5 年内超过 33000 英镑。
在控制治疗选择后,肾移植在重返工作岗位的潜力、劳动力收入和提前退休的风险方面优于透析。这种积极影响在移植后会随着时间的推移而增加。