Rakhmanova I V, Soldatsky Yu L, Matroskin A G, Marenich N S, Shelamova V N
N.I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia, 117997; N.I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia, 117997.
N.I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia, 117997; Morozovskzya City Children's Clinical Hospital, Moscow Health Department, Moscow, Russia, 111049.
Vestn Otorinolaringol. 2018;83(2):14-16. doi: 10.17116/otorino201883214-16.
The objective of the present study was the determination of the incidence of gastroesophageal reflux disease and the evaluation of its possible influence on the development and duration of chronic exudative otitis media in the children during the first year of life. A total of 141 infants at the age of 3 months presenting with exudative otitis media refractory to the conservative treatment throughout the first 1-1.5 months of life were available for the examination. The effectiveness of the anti-reflux therapy was estimated based on the middle ear condition (the presence or absence of exudate) within 3 and 6 months after the initiation of the treatment. The signs of aspiration of gastric chimus and gastroesophageal reflux disease were documented in 92% of the cases. The anti-reflux treatment during 3 months resulted in the disappearance of the manifestations of exudative otitis media in 43% of the patients. The further prolongation of such therapy up to 6 months allowed to normalize the state of the middle ear in 69% of the children although the remaining 40% failed to respond. It is concluded that the treatment of the children presenting with exudative otitis media during first year of life should be performed taking into consideration the possible involvement of gastroesophageal reflux disease in pathogenesis of this pathological condition.
本研究的目的是确定胃食管反流病的发病率，并评估其对一岁以内儿童慢性渗出性中耳炎的发生发展及病程的可能影响。共有141名3个月大的婴儿参与了检查，这些婴儿在出生后的前1 - 1.5个月内患有经保守治疗无效的渗出性中耳炎。根据治疗开始后3个月和6个月时的中耳状况（有无渗出液）评估抗反流治疗的效果。92%的病例记录到了胃内容物误吸和胃食管反流病的体征。3个月的抗反流治疗使43%的患者渗出性中耳炎症状消失。将这种治疗进一步延长至6个月，69%的儿童中耳状态恢复正常，尽管其余40%的儿童无反应。得出的结论是，对于一岁以内患有渗出性中耳炎的儿童进行治疗时，应考虑到胃食管反流病可能参与了这种病理状况的发病机制。
