Department of Dermatology, The George Washington Medical Faculty Associates, Washington, DC.
Dermatitis. 2018 May/Jun;29(3):112-119. doi: 10.1097/DER.0000000000000371.
Genital allergic contact dermatitis (ACD) is an uncommon disorder, yet it severely impairs the quality of life for both men and women. Because of cultural taboos, many patients self-treat and delay proper diagnosis before presenting to a provider. Diagnosis is further confounded by irritant contact dermatitis and other genital dermatoses, which can predispose to skin barrier dysfunction and allergen penetration. Genital ACD can present acutely with erythematous erosions and pruritus or chronically with lichenification. Patch testing helps determine the diagnosis and provide relief for the patient. Topical medications, including local anesthetics and corticosteroids, are the most common genital allergens. Other typical allergens include fragrances, preservatives, adhesives, dyes, and rubber products. Less commonly considered allergens include herbs, spices, and topical vehicle components. Here, we review the most common allergens for both men and women, discuss important patch-testing panels, and recommend safe products for patients with genital ACD.
生殖器过敏性接触性皮炎（ACD）是一种不常见的疾病，但它严重影响了男性和女性的生活质量。由于文化禁忌，许多患者自行治疗，并在向提供者就诊之前延迟了正确的诊断。诊断因刺激性接触性皮炎和其他生殖器皮肤病而更加复杂，这些疾病可能导致皮肤屏障功能障碍和过敏原渗透。生殖器 ACD 可急性表现为红斑性糜烂和瘙痒，也可慢性表现为苔藓样变。斑贴试验有助于确定诊断并为患者提供缓解。局部药物治疗，包括局部麻醉剂和皮质类固醇，是最常见的生殖器过敏原。其他常见的过敏原包括香料、防腐剂、粘合剂、染料和橡胶制品。不太常见的过敏原包括草药、香料和局部药物载体成分。在这里，我们回顾了男女两性最常见的过敏原，讨论了重要的斑贴试验组合，并为生殖器 ACD 患者推荐了安全的产品。
