Department of Dermatology, St. Luke's University Health Network, Easton, PA, USA.
Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Ann Med. 2021 Dec;53(1):2165-2177. doi: 10.1080/07853890.2021.2004322.
Internists are front-line health care providers that commonly provide the first encounter to patients for dermatological conditions, especially atopic dermatitis (AD). Internists need to be comfortable with managing mild-moderate AD in their practices. Criteria and guidelines established in dermatology literature are available to help the general practitioner diagnose and treat AD. AD is a systemic disease associated with multiple cutaneous and extra-cutaneous comorbidities that warrant screening by internists, especially mental health conditions. Environmental factors may play a role in the development or worsening of AD; however, there is currently no strong evidence to guide specific population- or clinic-based interventions for their avoidance. While food allergies are common in AD patients, the role of food allergens as an exacerbating factor for AD is controversial. Before starting any dietary modifications, careful evaluation should be performed by an allergist. If the patient is not well-controlled despite adequate topical therapies or is experiencing severe/worsening disease, early referral to dermatology is warranted to rule out confounding diagnoses and/or escalation to systemic therapies. Finally, it is important to recognise the racial disparities present in AD and address these when formulating treatment plans.Key messages:Confounding dermatoses, either instead of or in addition to AD, should be considered in treatment-refractory AD, and the appropriate workup may be initiated while awaiting dermatology referral.AD patients have multiple cutaneous and extra-cutaneous comorbidities that warrant screening by internists, especially mental health conditions.
内科医生是一线医疗保健提供者,通常为皮肤科疾病(尤其是特应性皮炎[AD])患者提供首次就诊。内科医生需要在其诊疗实践中熟练处理轻度至中度 AD。皮肤科文献中制定的标准和指南可帮助全科医生诊断和治疗 AD。AD 是一种与多种皮肤和皮肤外合并症相关的系统性疾病,需要内科医生进行筛查,尤其是心理健康状况。环境因素可能在 AD 的发展或恶化中起作用;然而,目前没有强有力的证据来指导特定人群或基于诊所的干预措施以避免这些因素。虽然 AD 患者中常见食物过敏,但食物过敏原作为 AD 加重因素的作用仍存在争议。在开始任何饮食改变之前,应由过敏症专家进行仔细评估。如果患者尽管接受了充分的局部治疗仍控制不佳或出现严重/恶化的疾病,应早期转诊至皮肤科以排除混淆诊断和/或升级为系统治疗。最后,重要的是要认识到 AD 中存在的种族差异,并在制定治疗计划时加以解决。
在治疗抵抗性 AD 中应考虑并发的(替代或附加于 AD 的)混淆性皮肤病,并在等待皮肤科转诊时可启动适当的检查。
AD 患者存在多种皮肤和皮肤外合并症,需要内科医生进行筛查,尤其是心理健康状况。