甲藻中的H1质子通道：难道仅仅用于生物发光吗？
H 1 Proton Channels in Dinoflagellates: Not Just for Bioluminescence?
作者信息
Kigundu Gabriel, Cooper Jennifer L, Smith Susan M E
机构信息
Department of Molecular and Cellular Biology, Kennesaw State University, 370 Paulding Avenue MD 1202, Kennesaw, Georgia, 30144.
出版信息
J Eukaryot Microbiol. 2018 Nov;65(6):928-933. doi: 10.1111/jeu.12627. Epub 2018 May 17.
Abstract
Bioluminescence in dinoflagellates is controlled by H 1 proton channels. Database searches of dinoflagellate transcriptomes and genomes yielded hits with sequence features diagnostic of all confirmed H 1, and show that H 1 is widely distributed in the dinoflagellate phylogeny including the basal species Oxyrrhis marina. Multiple sequence alignments followed by phylogenetic analysis revealed three major subfamilies of H 1 that do not correlate with presence of theca, autotrophy, geographic location, or bioluminescence. These data suggest that most dinoflagellates express a H 1 which has a function separate from bioluminescence. Sequence evidence also suggests that dinoflagellates can contain more than one H 1 gene.
摘要
甲藻中的生物发光由H1质子通道控制。对甲藻转录组和基因组进行数据库搜索，得到了具有所有已确认H1诊断性序列特征的结果，并表明H1广泛分布于甲藻系统发育中，包括基部物种尖尾藻。多重序列比对后进行系统发育分析，揭示了H1的三个主要亚家族，它们与甲藻的壳、自养、地理位置或生物发光无关。这些数据表明，大多数甲藻表达的H1具有与生物发光无关的功能。序列证据还表明，甲藻可以包含不止一个H1基因。
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